Professor Juan Mareque-Rivas

Professor

Chemistry

juan.mareque-rivas@swansea.ac.uk

Staff Office - 438
Third Floor
Grove Building
Singleton Campus

Available For Postgraduate Supervision

Research Links

https://orcid.org/0000-0002-7405-3338

ResearchGate

ResearcherID

About

Professor Mareque-Rivas graduated from the University of Strathclyde and Universidade de Santiago de Compostela with degrees in Chemistry and Applied Chemistry, specialising in inorganic, physical and pharmaceutical chemistry. He did his PhD (1995-98) in supramolecular chemistry at the University of Missouri-St Louis and then postdoctoral research at MIT in the laboratory of Steve Lippard in the area of metalloneurochemistry (1998-2000). He established his independent reseach group at the EastChem School of Chemistry of The University of Edinburgh (2000-11). He was recipient of an Ikerbasque Research Professorship to join the newly formed Centre for Cooperative Research in Biomaterials (CIC biomaGUNE) in San Sebastian, where he established and was Group Leader of the Theranostic Nanomedicine Laboratory (2011-18). On his return to the UK he was appointed at The University of Aberdeen to initiate the Biomedical Engineering programme at the School of Engineering. During 2016-17 he joined Swansea University as Research Professor, serving as Department Co-Head (2016-18) and Head of Research (2016-21) in the New Chemistry Department.

Areas Of Expertise

Biomaterials
Chemical Immunology
Materials and Polymers
Bioinorganic Chemistry
Supramolecular Chemistry
Biomimetic and Bioinspired Chemistry
Vaccines
Cancer Immunotherapy
Molecular Imaging

Career Highlights

Research

Chemical and materials science approaches provide major opportunities in medical research. Our main interest is in how they can be applied aiming controlled immune modulation to enhance the ability of the immune systems to prevent and treat diseases. This multidisciplinary research is geared towards development of theranostic (therapy + diagnosis) platforms for infectious, autoimmune diseases and cancer.

Development of immunomodulatory molecules and biomaterials. Our synthetic strategies exploit directed self-assembly and organization to minimise the number of synthetic steps and ensure efficient scale-up and easy adaptation in good manufacturing practice (GMP) production. Chemoselective and bioorthogonal ligation reactions and site‐specific conjugation approaches optimise presentation of (bio)molecules to the targets. We create also implantable biomaterial devices to locally modulate the immune system.

Studies at bioinorganic chemistry-chemical immunology interface. We investigate how certain structures and biological functions of inorganic biological substances (e.g. bioinorganic chemistry of iron, metalloenzymes and (bio)minerals with defined structures) modulate immune responses. We work with metallodrugs and prodrugs (e.g. platinum-based anticancer agents) and clinical imaging agents - redesigned/repurposed to trigger and amplify anti-tumor immunity, to exploit or reprogram the tumour microenvironment the enhance cancer immunotherapy and to monitor the immune system and the immunotherapy.

Development of chemically programmed vaccine platforms. Here our research seeks developing strategies to control vaccine assembly/disassembly at the biological target, to trigger biological activation by internal/external stimuli, to deploy combination therapy payloads, to promote cellular uptake of peptide neoantigens/mRNA to create personalised vaccines etc.

Publications

Research Highlights

Traini, G., Ruiz-de-Angulo, A., Blanco-Canosa, J., Bascarán, K., Molinaro, A., Silipo, A., Escors, D., & Mareque-Rivas, J. (2019). Cancer Immunotherapy of TLR4 Agonist-Antigen Constructs Enhanced with Pathogen-Mimicking Magnetite Nanoparticles and Checkpoint Blockade of PD-L1. Small, 15(4), 1803993
https://doi.org/10.1002/smll.201803993, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48048
Gondan, A., Ruiz-de-Angulo, A., Zabaleta, A., Blanco, N., Cobaleda-Siles, B., García-Granda, M., Padro, D., Llop, J., Arnaiz, B., Gato, M., Escors, D., Mareque-Rivas, J., & Mareque-Rivas, J. (2018). Effective cancer immunotherapy in mice by polyIC-imiquimod complexes and engineered magnetic nanoparticles. Biomaterials, 170, 95-115.
https://doi.org/10.1016/j.biomaterials.2018.04.003, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa39420
Castro, S., Ruggiero, E., Ruiz-de-Angulo, A., Rezabal, E., Mareque-Rivas, J., Lopez, X., López-Gallego, F., & Salassa, L. (2017). Riboflavin as a bioorthogonal photocatalyst for the activation of a PtIV prodrug. Chemical Science, 8(6), 4619-4625.
https://doi.org/10.1039/c7sc01109a, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa39419
Ruiz-de-Angulo, A., Zabaleta, A., Gómez-Vallejo, V., Llop, J., & Mareque-Rivas, J. (2016). Microdosed Lipid-Coated67Ga-Magnetite Enhances Antigen-Specific Immunity by Image Tracked Delivery of Antigen and CpG to Lymph Nodes. ACS Nano, 10(1), 1602-1618.
https://doi.org/10.1021/acsnano.5b07253, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30761
Hernández-Gil, J., Cobaleda-Siles, M., Zabaleta, A., Salassa, L., Calvo, J., & Mareque-Rivas, J. (2015). An Iron Oxide Nanocarrier Loaded with a Pt(IV) Prodrug and Immunostimulatory dsRNA for Combining Complementary Cancer Killing Effects. Advanced Healthcare Materials, 4(7), 1034-1042.
https://doi.org/10.1002/adhm.201500080, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30762

All Research

Journal Articles

Bilbao Asensio, M., Ruiz‐de‐Angulo, A., Arguinzoniz, A., Cronin, J., Llop, J., Zabaleta, A., Michue-Seijas, S., Sosnowska, D., Arnold, J., & Mareque-Rivas, J. (2022). Redox‐Triggered Nanomedicine via Lymphatic Delivery: Inhibition of Melanoma Growth by Ferroptosis Enhancement and a Pt(IV)‐Prodrug Chemoimmunotherapy Approach. Advanced Therapeutics, 6(2), 2200179
https://doi.org/10.1002/adtp.202200179, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61668
Ruiz-de-Angulo, A., Bilbao Asensio, M., Cronin, J., Evans, S., Clift, M., Llop, J., Feiner, I., Beadman, R., Bascarán, K., & Mareque-Rivas, J. (2020). Chemically Programmed Vaccines: Iron Catalysis in Nanoparticles Enhances Combination Immunotherapy and Immunotherapy-Promoted Tumor Ferroptosis. iScience, 23(9), 101499
https://doi.org/10.1016/j.isci.2020.101499, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55075
Traini, G., Ruiz-de-Angulo, A., Blanco-Canosa, J., Bascarán, K., Molinaro, A., Silipo, A., Escors, D., & Mareque-Rivas, J. (2019). Cancer Immunotherapy of TLR4 Agonist-Antigen Constructs Enhanced with Pathogen-Mimicking Magnetite Nanoparticles and Checkpoint Blockade of PD-L1. Small, 15(4), 1803993
https://doi.org/10.1002/smll.201803993, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48048
Gondan, A., Ruiz-de-Angulo, A., Zabaleta, A., Blanco, N., Cobaleda-Siles, B., García-Granda, M., Padro, D., Llop, J., Arnaiz, B., Gato, M., Escors, D., Mareque-Rivas, J., & Mareque-Rivas, J. (2018). Effective cancer immunotherapy in mice by polyIC-imiquimod complexes and engineered magnetic nanoparticles. Biomaterials, 170, 95-115.
https://doi.org/10.1016/j.biomaterials.2018.04.003, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa39420
Castro, S., Ruggiero, E., Ruiz-de-Angulo, A., Rezabal, E., Mareque-Rivas, J., Lopez, X., López-Gallego, F., & Salassa, L. (2017). Riboflavin as a bioorthogonal photocatalyst for the activation of a PtIV prodrug. Chemical Science, 8(6), 4619-4625.
https://doi.org/10.1039/c7sc01109a, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa39419
Ruiz-de-Angulo, A., Zabaleta, A., Gómez-Vallejo, V., Llop, J., & Mareque-Rivas, J. (2016). Microdosed Lipid-Coated67Ga-Magnetite Enhances Antigen-Specific Immunity by Image Tracked Delivery of Antigen and CpG to Lymph Nodes. ACS Nano, 10(1), 1602-1618.
https://doi.org/10.1021/acsnano.5b07253, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30761
Ruggiero, E., Garino, C., Mareque-Rivas, J., Habtemariam, A., & Salassa, L. (2016). Upconverting Nanoparticles Prompt Remote Near-Infrared Photoactivation of Ru(II)-Arene Complexes. Chemistry - A European Journal, 22(8), 2801-2811.
https://doi.org/10.1002/chem.201503991, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30763
Hernández-Gil, J., Cobaleda-Siles, M., Zabaleta, A., Salassa, L., Calvo, J., & Mareque-Rivas, J. (2015). An Iron Oxide Nanocarrier Loaded with a Pt(IV) Prodrug and Immunostimulatory dsRNA for Combining Complementary Cancer Killing Effects. Advanced Healthcare Materials, 4(7), 1034-1042.
https://doi.org/10.1002/adhm.201500080, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30762
Ruggiero, E., Hernández-Gil, J., Mareque-Rivas, J., & Salassa, L. (2015). Near infrared activation of an anticancer PtIVcomplex by Tm-doped upconversion nanoparticles. Chem. Commun., 51(11), 2091-2094.
https://doi.org/10.1039/C4CC07960D, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30764
Garaikoetxea Arguinzoniz, A., Gómez Blanco, N., Ansorena Legarra, P., Mareque-Rivas, J., & Mareque-Rivas, J. (2015). Enhanced cancer cell killing of a Pt(iv) prodrug promoted by outer-sphere coordination with polyethyleneimines. Dalton Trans., 44(16), 7135-7138.
https://doi.org/10.1039/C5DT00175G, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30766
Cobaleda-Siles, M., Henriksen-Lacey, M., de Angulo, A., Bernecker, A., Vallejo, V., Szczupak, B., Llop, J., Pastor, G., Plaza-Garcia, S., Jauregui-Osoro, M., Meszaros, L., & Mareque-Rivas, J. (2014). An Iron Oxide Nanocarrier for dsRNA to Target Lymph Nodes and Strongly Activate Cells of the Immune System. Small, n/a-n/a.
https://doi.org/10.1002/smll.201401353, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30767
Arguinzoniz, A., Ruggiero, E., Habtemariam, A., Hernández-Gil, J., Salassa, L., & Mareque-Rivas, J. (2014). Light Harvesting and Photoemission by Nanoparticles for Photodynamic Therapy. Particle & Particle Systems Characterization, 31(1), 46-75.
https://doi.org/10.1002/ppsc.201300314, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30770
Ruggiero, E., Habtemariam, A., Yate, L., Mareque-Rivas, J., Salassa, L., & Mareque-Rivas, J. (2014). Near infrared photolysis of a Ru polypyridyl complex by upconverting nanoparticles. Chemical Communications, 50(14), 1715
https://doi.org/10.1039/C3CC47601D, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30778
Infante, I., Azpiroz, J., Blanco, N., Ruggiero, E., Ugalde, J., Mareque-Rivas, J., & Salassa, L. (2014). Quantum Dot Photoactivation of Pt(IV) Anticancer Agents: Evidence of an Electron Transfer Mechanism Driven by Electronic Coupling. The Journal of Physical Chemistry C, 118(16), 8712-8721.
https://doi.org/10.1021/jp501447q, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30777
Hernández-Gil, J., Ferrer, S., Castiñeiras, A., Liu-González, M., Lloret, F., Ribes, Á., Čoga, L., Bernecker, A., & Mareque-Rivas, J. (2014). Two Novel Ternary Dicopper(II) μ-Guanazole Complexes with Aromatic Amines Strongly Activated by Quantum Dots for DNA Cleavage. Inorganic Chemistry, 53(1), 578-593.
https://doi.org/10.1021/ic4027249, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30769
Maldonado, C., Salassa, L., Gomez-Blanco, N., & Mareque-Rivas, J. (2013). Nano-functionalization of metal complexes for molecular imaging and anticancer therapy. Coordination Chemistry Reviews, 257(19-20), 2668-2688.
https://doi.org/10.1016/j.ccr.2013.04.014, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30771
Maldonado, C., Gómez-Blanco, N., Jauregui-Osoro, M., Brunton, V., Yate, L., & Mareque-Rivas, J. (2013). QD-filled micelles which combine SPECT and optical imaging with light-induced activation of a platinum(iv) prodrug for anticancer applications. Chemical Communications, 49(38), 3985
https://doi.org/10.1039/C3CC39104C, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30772
Hernández-Gil, J., Ferrer, S., Salvador, E., Calvo, J., Garcia-España, E., & Mareque-Rivas, J. (2013). A dinucleating ligand which promotes DNA cleavage with one and without a transition metal ion. Chemical Communications, 49(35), 3655
https://doi.org/10.1039/C3CC39067E, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30773
Blanco, N., Jauregui-Osoro, M., Cobaleda-Siles, M., Maldonado, C., Henriksen-Lacey, M., Padro, D., Clark, S., & Mareque-Rivas, J. (2012). Iron oxide-filled micelles as ligands for fac-[M(CO)3]+ (M = 99mTc, Re). Chemical Communications, 48(35), 4211
https://doi.org/10.1039/C2CC31045G, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30774
Maldonado, C., Touceda-Varela, A., Jones, A., & Mareque-Rivas, J. (2011). A turn-on fluorescence sensor for cyanide from mechanochemical reactions between quantum dots and copper complexes. Chemical Communications, 47(42), 11700
https://doi.org/10.1039/C1CC14565G, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30775
Hernández-Gil, J., Llusar, S., Maldonado, C., & Mareque-Rivas, J. (2011). Synergy between quantum dots and 1,10-phenanthroline–copper(ii) complex towards cleaving DNA. Chemical Communications, 47(10), 2955
https://doi.org/10.1039/C0CC04163G, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30776
Blanco, N., Maldonado, C., & Mareque-Rivas, J. (2009). Effective photoreduction of a Pt(iv) complex with quantum dots: a feasible new light-induced method of releasing anticancer Pt(ii) drugs. Chemical Communications(35), 5257
https://doi.org/10.1039/B910000H, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30782
Ganesh, V., Bodewits, K., Bartholdson, S., Natale, D., Campopiano, D., Mareque-Rivas, J., & Mareque-Rivas, J. (2009). Effective Binding and Sensing of Lipopolysaccharide: Combining Complementary Pattern Recognition Receptors. Angewandte Chemie International Edition, 48(2), 356-360.
https://doi.org/10.1002/anie.200804168, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30781
Touceda-Varela, A., Stevenson, E., Galve-Gasión, J., Dryden, D., & Mareque-Rivas, J. (2008). Selective turn-on fluorescence detection of cyanide in water using hydrophobic CdSe quantum dots. Chemical Communications(17), 1998
https://doi.org/10.1039/B716194H, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30780
Natale, D. & Mareque-Rivas, J. (2008). The combination of transition metal ions and hydrogen-bonding interactions. Chem. Commun.(4), 425-437.
https://doi.org/10.1039/B709650J, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30783
Gupta, M., Caniard, A., Touceda-Varela, A., Campopiano, D., & Mareque-Rivas, J. (2008). Nitrilotriacetic Acid-Derivatized Quantum Dots for Simple Purification and Site-Selective Fluorescent Labeling of Active Proteins in a Single Step. Bioconjugate Chemistry, 19(10), 1964-1967.
https://doi.org/10.1021/bc800273j, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30787
Ganesh, V., Calatayud Sanz, M., & Mareque-Rivas, J. (2007). Effective anion sensing based on the ability of copper to affect electron transport across self-assembled monolayers. Chemical Communications(47), 5010
https://doi.org/10.1039/B712857F, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30786
Feng, G., Natale, D., Prabaharan, R., Mareque-Rivas, J., & Williams, N. (2006). Efficient Phosphodiester Binding and Cleavage by a ZnII Complex Combining Hydrogen-Bonding Interactions and Double Lewis Acid Activation. Angewandte Chemie International Edition, 45(42), 7056-7059.
https://doi.org/10.1002/anie.200602532, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30784
Feng, G., Mareque-Rivas, J., Torres Martín de Rosales, R., & Williams, N. (2005). A Highly Reactive Mononuclear Zn(II) Complex for Phosphodiester Cleavage. Journal of the American Chemical Society, 127(39), 13470-13471.
https://doi.org/10.1021/ja054003t, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30785
Mareque-Rivas, J., Prabaharan, R., & Martín de Rosales, R. (2004). Relative importance of hydrogen bonding and coordinating groups in modulating the zinc–water acidity. Chem. Commun.(1), 76-77.
https://doi.org/10.1039/B310956A, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30788

Supervision

Multimodal nanomaterials for combating antimicrobial resistance (current)

PhD

Other supervisor: Dr Martin Gill
Modified Phospholipids in Synergy with Small Molecules and Iron Oxide for Cancer Immunotherapy (current)

PhD

Other supervisor: Prof Owen Guy
Development of biomaterials for development of enhanced vaccines against infectious disease and cancer (current)

PhD

Other supervisor: Dr James Cronin
Biodegradable Nanovectors for the Treatment of Advanced Ovarian Cancer. (awarded 2024)

PhD

Other supervisor: Prof Lewis Francis
Polymers of Intrinsic Microporosity for Heterogeneous Base Catalysis (awarded 2023)

PhD

Other supervisor: Dr Mariolino Carta
Biomaterial-based transdermal and implantable vaccine delivery systems for cancer immunotherapy (awarded 2022)

PhD

Other supervisor: Prof Owen Guy
Investigation of the photophysical and DNA binding properties of [Ru(5,5’-dmbpy)2(10,11-dmdppz)]2+ and [Ru(bpy)2(10,11-dmdppz)]2+ (awarded 2023)

MSc

Other supervisor: Dr Martin Gill
Platinum(IV) Prodrugs Conjugated to DSPE-PEG for Development of Iron Oxide Nanoparticle Micelles for Multimodal Cancer Therapy (awarded 2024)

MSc

Other supervisor: Dr Mariolino Carta

Taught Modules

CH-127 Chemical Practice

This module will introduce students to the three broad employment areas for chemistry: research, teaching or industrial positions. The lecture portion will cover fundamental aspects of being a professional chemist including safety, report writing, project management, and teaching skills. Students will attend research seminars and workshops, industrial field trips, and supervise school pupils in the laboratory. Assessment will be by coursework and a written report.
CH-232 Further Inorganic Chemistry

This module will continue discussion of concepts traditionally considered to be inorganic chemistry studying the structure and bonding of main group and transition metal compounds and major classes of reactions. Symmetry and group theory will also be introduced in this module. Note: it is expected that material, techniques and skills covered in the course of this module will require understanding of any prior module. The module will have a variety of formative assessment opportunities and summative assessments that include writing of technical reports, a presentation, homework, workshops, and an exam.
CH-340 Advanced Topics in Inorganic and Materials Chemistry

This module will provide a fuller and more comprehensive understanding of inorganic chemistry built upon the principles introduced in Years 1 and 2. It will illustrate how various classes of inorganic compounds and materials, including coordination compounds, cluster compounds, organometallic compounds, nanomaterials, porous materials, semiconductors and supramolecular systems are prepared and characterised. The student will gain an understanding of inorganic materials properties and of the principles and experimental techniques that underpin their synthesis. The module will illustrate specific applications of inorganic materials and will show the importance and use of inorganic chemistry in biological applications.
CH-344 Chemistry Project

3rd year projects are the opportunity to bring all you've learnt during your degree together and apply that knowledge to solve a problem. In Swansea these projects can be embedded in active research groups across the colleges of science, engineering or medicine, allowing you to build a network and experience in your chosen specialism within the chemical sciences. These projects are your opportunity to demonstrate to employers that you have a full understanding of your course and are able to direct your own studies, manage an independent research project and effectively communicate your findings. This selection suggests an interest in a project embedded within a research group in engineering, focusing on materials chemistry or chemical engineering
CH-349 Integrated Topics in Chemistry

This module gives students the opportunity to explore options within Chemistry, giving opportunity to apply prior learning to advanced research topics and allowing students to pursue more specialised topics related to their research interests and aligned with the research areas represented within the Department. Study areas available will include advanced spectroscopic techniques, the application of instrumentation in chemistry, as well as more advanced synthetic pathways and a return to more integrated study of the traditional branches of organic/inorganic/physical chemistry. The module will also include a mandatory employability component. Classes will be supported with workshops which will help students gain a thorough understanding of the integrated nature of Chemistry at an advanced level. Where possible, topics will be taught using relevant examples from primary literature, encouraging students to evaluate and appraise a range of primary literature sources and locate appropriate new sources. The module is designed to be flexible to allow the content to vary with the research areas represented within the Department and wider university.
CH-409 MChem Research Project

MChem projects are the defining feature of the integrated masters with a chance to contribute research work of potentially publishable standard to an active research group within the University. In Swansea these projects can be embedded in active research groups across the Faculty of Science and Engineering or the Faculty of Medicine, Health and Life Science, allowing you to build a network and experience in your chosen specialism within the chemical sciences. These projects are an excellent way of managing the transition on to your next destination after undergraduate study, whether that is a postgraduate research studentship or into employment. The skills developed in the MChem projects demonstrate the ability to successfully deliver all aspects of a 60 credit research project and on exit you will have demonstrated the academic equivalence and begun developing the other skills required for entry into professional development schemes leading to chartership. This selection suggests an interest in a project embedded within a research group in science, focusing on straight chemistry, or interacting and collaborating with another department such as bioscience, geography, physics, maths or computer science.
CH-413 Advanced Integrated Topics in Chemistry Part 2

This module gives students the opportunity to explore options within Chemistry, giving opportunity to apply prior learning to advanced research topics and allowing students to pursue more specialised topics related to their research interests and aligned with the research areas represented within the Department. Study areas available will include advanced spectroscopic techniques, the application of instrumentation in chemistry, as well as more advanced synthetic pathways and a return to more integrated study of the traditional branches of organic/inorganic/physical chemistry. Classes will be supported with workshops which will help students gain a thorough understanding of the integrated nature of Chemistry at an advanced level. Where possible, topics will be taught using relevant examples from primary literature, encouraging students to evaluate and appraise a range of primary literature sources and locate appropriate new sources. The module is designed to be flexible to allow the content to vary with the research areas represented within the Department.

Professor Juan Mareque-Rivas

Email address

Research Links

About

Areas Of Expertise

Career Highlights

Publications

Research Highlights

All Research

Journal Articles

Supervision

Multimodal nanomaterials for combating antimicrobial resistance (current)

Modified Phospholipids in Synergy with Small Molecules and Iron Oxide for Cancer Immunotherapy (current)

Development of biomaterials for development of enhanced vaccines against infectious disease and cancer (current)

Biodegradable Nanovectors for the Treatment of Advanced Ovarian Cancer. (awarded 2024)

Polymers of Intrinsic Microporosity for Heterogeneous Base Catalysis (awarded 2023)

Biomaterial-based transdermal and implantable vaccine delivery systems for cancer immunotherapy (awarded 2022)

Investigation of the photophysical and DNA binding properties of [Ru(5,5’-dmbpy)2(10,11-dmdppz)]2+ and [Ru(bpy)2(10,11-dmdppz)]2+ (awarded 2023)

Platinum(IV) Prodrugs Conjugated to DSPE-PEG for Development of Iron Oxide Nanoparticle Micelles for Multimodal Cancer Therapy (awarded 2024)

Taught Modules

CH-127 Chemical Practice

CH-232 Further Inorganic Chemistry

CH-340 Advanced Topics in Inorganic and Materials Chemistry

CH-344 Chemistry Project

CH-349 Integrated Topics in Chemistry

CH-409 MChem Research Project

CH-413 Advanced Integrated Topics in Chemistry Part 2