Professor Venkat Kanamarlapudi

Professor of Molecular Cell Biology

Biomedical Sciences

+44 (0) 1792 295012

k.venkateswarlu@swansea.ac.uk

Office CNH - 008
Ground Floor
Institute of Life Science 2
Singleton Campus

Available For Postgraduate Supervision

Research Links

https://orcid.org/0000-0002-8739-1483

ResearchGate

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ResearcherID

Scopus

About

Venkateswarlu Kanamarlapudi is a Professor of Molecular Cell Biology and Pharmacology at Swansea University Medical School.

Prof. Kanamarlapudi main research interests lie in understanding GPCR-, inositol lipids- and small GTPases-mediated cell signalling in health and disease. His group recent efforts have also been focussed on the development of targeted therapy for pancreatic cancer and the improvement of LVADs.

Prof. Kanamarlapudi obtained BSc (Biology & Chemistry) from Acharya Nagarjuna University, MSc (Biochemistry) from the University of Hyderabad, MTech (Biotechnology) from IIT-Kharagpur and PhD from the University of Sheffield (researched on antifungal drugs mode of action and fungal resistance under Prof. Steve Kelly’s supervision).

Before Joining Swansea, Prof. Kanamarlapudi worked as a research scientist at AstraZeneca (India) on anti-microbial drugs, post-doctoral researcher in the School of Biochemistry at the University of Bristol on the regulation of ARF cell signalling by inositol lipids, and BBSRC David Phillips Research Fellow and Lecturer in School of Physiology and Pharmacology at the University of Bristol on ARF and inositol lipid signalling in health and disease.

Based on his research accomplishments, Prof. Kanamarlapudi has been elected as a fellow of several learned societies (FRSB, FRSC, FLSW, FABAP, FAPAS, FNABS) and received DSc (Doctor of Science) from Swansea University.

Areas Of Expertise

Biochemistry
Cell Biology
Pharmacology
Cardiovascular
Cancer
Diabetes
Cell Signalling
Molecular Medicine

Career Highlights

Teaching Interests

Membrane Trafficking

Biochemistry Literature Review and Communication

Biomolecular Research Project

Postgraduate Training

Research Award Highlights Collaborations

Publications

Research Highlights

Guo, Y. & Kanamarlapudi, V. (2023). Molecular Analysis of SARS-CoV-2 Spike Protein-Induced Endothelial Cell Permeability and vWF Secretion. International Journal of Molecular Sciences, 24(6), 5664
https://doi.org/10.3390/ijms24065664, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63098
http://dx.doi.org/10.3390/ijms24065664
Row, P., Jannoo, R., Xia, Z., Row, P., & Kanamarlapudi, V. (2023). Targeting of the Interleukin-13 Receptor (IL-13R)α2 Expressing Prostate Cancer by a Novel Hybrid Lytic Peptide. Biomolecules, 13(2), 356
https://doi.org/10.3390/biom13020356, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63097
http://dx.doi.org/10.3390/biom13020356
Kanamarlapudi, V., Tamaddon Jahromi, S., & Murphy, K. (2022). ADP-ribosylation factor 6 expression increase in oesophageal adenocarcinoma suggests a potential biomarker role for it. PLOS ONE, 17(2), e0263845
https://doi.org/10.1371/journal.pone.0263845, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60111
Reed, J., Bain, S., & Kanamarlapudi, V. (2021). A Review of Current Trends with Type 2 Diabetes Epidemiology, Aetiology, Pathogenesis, Treatments and Future Perspectives. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 14, 3567-3602.
https://doi.org/10.2147/dmso.s319895, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57318
Francis, W., Owens, S., Kanamarlapudi, V., & Xia, Z. (2021). Role of hypoxia inducible factor 1alpha in cobalt nanoparticle induced cytotoxicity of human THP-1 macrophages. Biomaterials Translational, 2(2), 143-150.
https://doi.org/10.12336/biomatertransl.2021.02.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57975
Sargent, C., Perkins, I., Kanamarlapudi, V., Moriarty, C., & Ali, S. (2021). Hemodilution Increases the Susceptibility of Red Blood Cells to Mechanical Shear Stress During In Vitro Hemolysis Testing. ASAIO Journal, 67(6), 632-641.
https://doi.org/10.1097/mat.0000000000001280, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57577
Reed, J., Bain, S., & Kanamarlapudi, V. (2020). Recent advances in understanding the role of glucagon-like peptide 1. F1000Research, 9, 239
https://doi.org/10.12688/f1000research.20602.1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54102
Chiou, T., Long, P., Schumann-Gillett, A., Kanamarlapudi, V., Haas, S., Harvey, K., O’Mara, M., Blas, A., Kalscheuer, V., & Harvey, R. (2019). Mutation p.R356Q in the Collybistin Phosphoinositide Binding Site Is Associated With Mild Intellectual Disability. Frontiers in Molecular Neuroscience, 12
https://doi.org/10.3389/fnmol.2019.00060, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50064
Eva, R., Koseki, H., Kanamarlapudi, V., & Fawcett, J. (2017). EFA6 regulates selective polarised transport and axon regeneration from the axon initial segment. Journal of Cell Science, 130(21), 3663-3675.
https://doi.org/10.1242/jcs.207423, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35637
John, D., Williams, L., Kanamarlapudi, V., Humphrey, T., & Wilkinson, T. (2017). The Bacterial Species Campylobacter jejuni Induce Diverse Innate Immune Responses in Human and Avian Intestinal Epithelial Cells. Frontiers in Microbiology, 8
https://doi.org/10.3389/fmicb.2017.01840, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35842
Chan, C., Pieper, I., Robinson, C., Friedmann, Y., Kanamarlapudi, V., & Thornton, C. (2017). Shear Stress-Induced Total Blood Trauma in Multiple Species. Artificial Organs
https://doi.org/10.1111/aor.12932, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31746
Thornton, C., Cronin, J., Kanamarlapudi, V., & Sheldon, M. (2016). Signal transducer and activator of transcription-3 licenses Toll-like receptor 4-dependent interleukin (IL)-6 and IL-8 production via IL-6 receptor-positive feedback in endometrial cells. Mucosal Immunology, 9(4), 1125-1136.
https://doi.org/10.1038/mi.2015.131, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25017
http://www.nature.com/mi/journal/vaop/ncurrent/full/mi2015131a.html
Thompson, A., Stephens, J., Bain, S., & Kanamarlapudi, V. (2016). Molecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor Internalisation. PLOS ONE, 11(4), e0154229
https://doi.org/10.1371/journal.pone.0154229, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27352
Venkateswarlu, K., Uma, D., Andrés, L., & Kanamarlapudi, V. (2016). Luteinizing hormone/chorionic gonadotrophin receptor overexpressed in granulosa cells from polycystic ovary syndrome ovaries is functionally active. Reproductive BioMedicine Online
https://doi.org/10.1016/j.rbmo.2016.03.003, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26971
Thompson, A. & Kanamarlapudi, V. (2015). Distinct Regions in the C-Terminus Required for GLP-1R Cell Surface Expression, Activity and Internalisation. Molecular and Cellular Endocrinology, 413, 66-77.
https://doi.org/10.1016/j.mce.2015.06.012, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa22217
Franssen, E., Zhao, R., Koseki, H., Kanamarlapudi, V., Hoogenraad, C., Eva, R., Fawcett, J., & Kanamarlapudi, V. (2015). Exclusion of Integrins from CNS Axons Is Regulated by Arf6 Activation and the AIS. Journal of Neuroscience, 35(21), 8359-8375.
https://doi.org/10.1523/JNEUROSCI.2850-14.2015, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa21767
Thompson, A. & Kanamarlapudi, V. (2015). Agonist-induced internalisation of the glucagon-like peptide-1 receptor is mediated by the Gαq pathway. Biochemical Pharmacology, 93(1), 72-84.
https://doi.org/10.1016/j.bcp.2014.10.015, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19150
Chan, C., Pieper, I., Fleming, S., Friedmann, Y., Foster, G., Hawkins, K., Thornton, C., & Kanamarlapudi, V. (2014). The Effect of Shear Stress on the Size, Structure, and Function of Human von Willebrand Factor. Artificial Organs, 38(9), 741-750.
https://doi.org/10.1111/aor.12382, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18740
Thompson, A. & Kanamarlapudi, V. (2014). The regions within the N-terminus critical for human glucagon like peptide-1 receptor (hGLP-1R) cell Surface expression. Scientific Reports, 4, 7410
https://doi.org/10.1038/srep07410, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19782
Davies, J., Tamaddon-Jahromi, S., Jannoo, R., & Kanamarlapudi, V. (2014). Cytohesin 2/ARF6 regulates preadipocyte migration through the activation of ERK1/2. Biochemical Pharmacology, 92(4), 651-660.
https://doi.org/10.1016/j.bcp.2014.09.023, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18768
Konstantinou, D., Lei, M., Xia, Z., & Kanamarlapudi, V. (2014). Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor. Cell Biology International, 39(4), 502-507.
https://doi.org/10.1002/cbin.10409, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19760
Kanamarlapudi, V. & Kanamarlapudi, V. (2014). Exchange factor EFA6R requires C-terminal targeting to the plasma membrane to promote cytoskeletal rearrangement through the activation of ARF6. Journal of Biological Chemistry, 289(48), 33378-33390.
https://doi.org/10.1074/jbc.M113.534156, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18668
Francis, W., Owens, S., Xia, Z., & Kanamarlapudi, V. (2014). The temporal expression of estrogen receptor alpha-36 and runx2 in human bone marrow derived mesenchymal stromal cells during osteogenesis. Biochem Biophys Res Commun
https://doi.org/10.1016/j.bbrc.2014.09.111, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19126
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=25281901
Davies, J., Bain, S., & Kanamarlapudi, V. (2014). ADP-ribosylation factor 6 regulates endothelin-1-induced lipolysis in adipocytes. BIOCHEMICAL PHARMACOLOGY, 90(4), 406-413.
https://doi.org/10.1016/j.bcp.2014.06.012, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18415
Tu, Y., Xue, H., Francis, W., Davies, A., Pallister, I., Kanamarlapudi, V., & Xia, Z. (2013). Lactoferrin inhibits dexamethasone-induced chondrocyte impairment from osteoarthritic cartilage through up-regulation of extracellular signal-regulated kinase 1/2 and suppression of FASL, FAS, and Caspase 3. Biochemical and Biophysical Research Communications, 441(1), 249-255.
https://doi.org/10.1016/j.bbrc.2013.10.047, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16395
Aiysha Thompson, K. & Kanamarlapudi, V. (2013). Type 2 Diabetes Mellitus and Glucagon Like Peptide-1 Receptor Signalling. Clinical & Experimental Pharmacology, 03(04)
https://doi.org/10.4172/2161-1459.1000138, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27395
Kanamarlapudi, V., Owens, S., Saha, K., Pope, R., & Mundell, S. (2012). ARF6-Dependent Regulation of P2Y Receptor Traffic and Function in Human Platelets. PLoS ONE, 7(8), e43532
https://doi.org/10.1371/journal.pone.0043532, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12399
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0043532
Eva, R., Crisp, S., Marland, J., Norman, J., Kanamarlapudi, V., ffrench-Constant, C., & Fawcett, J. (2012). ARF6 Directs Axon Transport and Traffic of Integrins and Regulates Axon Growth in Adult DRG Neurons. The Journal of Neuroscience, 32(30), 10352-10364.
https://doi.org/10.1523/JNEUROSCI.1409-12.2012, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12274
Kanamarlapudi, V., Owens, S., Lartey, J., & Bernal, A. (2012). ADP-Ribosylation Factor 6 Expression and Activation Are Reduced in Myometrium in Complicated Pregnancies. PLoS ONE, 7(5), e37954
https://doi.org/10.1371/journal.pone.0037954, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa11278
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0037954
Kanamarlapudi, V., Thompson, A., Kelly, E., & Bernal, A. (2012). ARF6 Activated by the LHCG Receptor through the Cytohesin Family of Guanine Nucleotide Exchange Factors Mediates the Receptor Internalization and Signaling. Journal of Biological Chemistry, 287(24), 20443
https://doi.org/10.1074/jbc.M112.362087, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa11277
Kalscheuer, V., Musante, L., Fang, C., Hoffmann, K., Fuchs, C., Carta, E., Deas, E., Venkateswarlu, K., Menzel, C., Ullmann, R., Tommerup, N., Dalprà, L., Tzschach, A., Selicorni, A., Lüscher, B., Ropers, H., Harvey, K., Harvey, R., & Kanamarlapudi, V. (2009). A balanced chromosomal translocation disrupting ARHGEF9 is associated with epilepsy, anxiety, aggression, and mental retardation. Human Mutation, 30(1), 61-68.
https://doi.org/10.1002/humu.20814, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10516
Stewart, R., Song, L., Carter, S., Sigalas, C., Zaccai, N., Kanamarlapudi, V., Bhat, M., Takeshima, H., & Sitsapesan, R. (2008). Single-Channel Characterization of the Rabbit Recombinant RyR2 Reveals a Novel Inactivation Property of Physiological Concentrations of ATP. Journal of Membrane Biology, 222(2), 65-77.
https://doi.org/10.1007/s00232-008-9102-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10515
Venkateswarlu, K., Brandom, K., Yun, H., & Kanamarlapudi, V. (2007). PI-3-kinase-dependent membrane recruitment of centaurin- 2 is essential for its effect on ARF6-mediated actin cytoskeleton reorganisation. Journal of Cell Science, 120(5), 792-801.
https://doi.org/10.1242/jcs.03373, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1354
Bouschet, T., Martin, S., Kanamarlapudi, V., Mundell, S., & Henley, J. (2007). The calcium-sensing receptor changes cell shape via a beta-arrestin-1 ARNO ARF6 ELMO protein network. Journal of Cell Science, 120(15), 2489-2497.
https://doi.org/10.1242/jcs.03469, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25090
Kanumilli, S., Tringham, E., Payne, C., Dupere, J., Venkateswarlu, K., Usowicz, M., & Kanamarlapudi, V. (2006). Alternative splicing generates a smaller assortment of CaV2.1 transcripts in cerebellar Purkinje cells than in the cerebellum. Physiological Genomics, 24(2), 86-96.
https://doi.org/10.1152/physiolgenomics.00149.2005, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25091
Lawrence, J., Mundell, S., Yun, H., Kelly, E., Venkateswarlu, K., & Kanamarlapudi, V. (2005). Centaurin- 1, an ADP-Ribosylation Factor 6 GTPase Activating Protein, Inhibits 2-Adrenoceptor Internalization. Molecular Pharmacology, 67(6), 1822-1828.
https://doi.org/10.1124/mol.105.011338, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25092
Kanamarlapudi, V. & Kanamarlapudi, V. (2005). Centaurin-alpha(1) and KIF13B kinesin motor protein interaction in ARF6 signalling. Biochemical Society Transactions, 33
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25093
Venkateswarlu, K. & Kanamarlapudi, V. (2005). GTPases Regulating Membrane Dynamics. Analysis of the Interaction Between Cytohesin 2 and IPCEF1 (pp. 252-266).
https://doi.org/10.1016/s0076-6879(05)04024-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25094
Gunn-Moore, F., Welsh, G., Herron, L., Brannigan, F., Venkateswarlu, K., Gillespie, S., Brandwein-Gensler, M., Madan, R., Tavare, J., Brophy, P., Prystowsky, M., Guild, S., & Kanamarlapudi, V. (2005). A novel 4.1 ezrin radixin moesin (FERM)-containing protein, ‘Willin’. FEBS Letters, 579(22), 5089-5094.
https://doi.org/10.1016/j.febslet.2005.07.097, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25095
Kanamarlapudi, V. & Kanamarlapudi, V. (2005). Centaurin-α1 and KIF13B kinesin motor protein interaction in ARF6 signalling. Biochemical Society Transactions, 33(6), 1279
https://doi.org/10.1042/BST20051279, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26972
http://europepmc.org/abstract/med/16246098
Venkateswarlu, K. & Kanamarlapudi, V. (2005). Centaurin- 1 interacts directly with kinesin motor protein KIF13B. Journal of Cell Science, 118(11), 2471-2484.
https://doi.org/10.1242/jcs.02369, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1355
Lockyer, P., Bottomley, J., Reynolds, J., McNulty, T., Venkateswarlu, K., Potter, B., Dempsey, C., Cullen, P., & Kanamarlapudi, V. (2004). Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1 IP4BP and GAP1 m result from the GAP1 IP4BP PH domain directing plasma membrane targeting. Current Biology, 7(12), 1007-1010.
https://doi.org/10.1016/S0960-9822(06)00423-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52040
Venkateswarlu, K. & Kanamarlapudi, V. (2003). Centaurin- 1 Is an in Vivo Phosphatidylinositol 3,4,5-Trisphosphate-dependent GTPase-activating Protein for ARF6 That Is Involved in Actin Cytoskeleton Organization. Journal of Biological Chemistry, 279(8), 6205-6208.
https://doi.org/10.1074/jbc.C300482200, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1356
Venkateswarlu, K. & Kanamarlapudi, V. (2003). Interaction Protein for Cytohesin Exchange Factors 1 (IPCEF1) Binds Cytohesin 2 and Modifies Its Activity. Journal of Biological Chemistry, 278(44), 43460-43469.
https://doi.org/10.1074/jbc.M304078200, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1357
Kanumilli, S., Toms, N., Venkateswarlu, K., Mellor, H., Roberts, P., & Kanamarlapudi, V. (2002). Functional coupling of rat metabotropic glutamate 1a receptors to phospholipase D in CHO cells: involvement of extracellular Ca2+, protein kinase C, tyrosine kinase and Rho-A. Neuropharmacology, 42(1), 1-8.
https://doi.org/10.1016/s0028-3908(01)00161-7, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25096
Bobe, R., Wilde, J., Maschberger, P., Venkateswarlu, K., Cullen, P., Siess, W., Watson, S., & Kanamarlapudi, V. (2001). Phosphatidylinositol 3-kinase-dependent translocation of phospholipase Cgamma2 in mouse megakaryocytes is independent of Bruton tyrosine kinase translocation. Blood, 97(3), 678-684.
https://doi.org/10.1182/blood.V97.3.678, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25097
Lamb, D., Kaderbhai, N., Venkateswarlu, K., Kelly, D., Kelly, S., Kaderbhai, M., & Kanamarlapudi, V. (2001). Human Sterol 14α-Demethylase Activity Is Enhanced by the Membrane-Bound State of Cytochrome b5. Archives of Biochemistry and Biophysics, 395(1), 78-84.
https://doi.org/10.1006/abbi.2001.2566, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25098
Dubois, T., Kerai, P., Zemlickova, E., Howell, S., Jackson, T., Venkateswarlu, K., Cullen, P., Theibert, A., Larose, L., Roach, P., Aitken, A., & Kanamarlapudi, V. (2001). Casein Kinase I Associates with Members of the Centaurin-alpha Family of Phosphatidylinositol 3,4,5-Trisphosphate-binding Proteins. Journal of Biological Chemistry, 276(22), 18757-18764.
https://doi.org/10.1074/jbc.M010005200, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25099
Lamb, D., Warrilow, A., Venkateswarlu, K., Kelly, D., Kelly, S., & Kanamarlapudi, V. (2001). Activities and Kinetic Mechanisms of Native and Soluble NADPH–Cytochrome P450 Reductase. Biochemical and Biophysical Research Communications, 286(1), 48-54.
https://doi.org/10.1006/bbrc.2001.5338, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25100
Venkateswarlu, K., Cullen, P., & Kanamarlapudi, V. (2000). Signalling via ADP-ribosylation factor 6 lies downstream of phosphatidylinositide 3-kinase. Biochemical Journal, 345(3), 719
https://doi.org/10.1042/0264-6021:3450719, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25101
Cullen, P., Venkateswarlu, K., & Kanamarlapudi, V. (1999). Potential regulation of ADP-ribosylation factor 6 signalling by phosphatidylinositol 3,4,5-trisphosphaee. Biochemical Society Transactions, 27
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25102
Venkateswarlu, K., Cullen, P., & Kanamarlapudi, V. (1999). Molecular Cloning and Functional Characterization of a Human Homologue of Centaurin-α. Biochemical and Biophysical Research Communications, 262(1), 237-244.
https://doi.org/10.1006/bbrc.1999.1065, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25103
Lockyer, P., Wennstrom, S., Kupzig, S., Venkateswarlu, K., Downward, J., Cullen, P., & Kanamarlapudi, V. (1999). Identification of the Ras GTPase-activating protein GAP1m as a phosphatidylinositol-3,4,5-trisphosphate-binding protein in vivo. Current Biology, 9(5), 265-269.
https://doi.org/10.1016/s0960-9822(99)80116-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25104
Venkateswarlu, K., Oatey, P., Tavare, J., Jackson, T., Cullen, P., & Kanamarlapudi, V. (1999). Identification of centaurin-α1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1. Biochemical Journal, 340(2), 359
https://doi.org/10.1042/0264-6021:3400359, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25105
Lamb, D., Kelly, D., Venkateswarlu, K., Manning, N., Bligh, H., Schunck, W., Kelly, S., & Kanamarlapudi, V. (1999). Generation of a Complete, Soluble, and Catalytically Active Sterol 14α-Demethylase−Reductase Complex†. Biochemistry, 38(27), 8733-8738.
https://doi.org/10.1021/bi9825089, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25106
Venkateswarlu, K., Gunn-Moore, F., Tavare, J., Cullen, P., & Kanamarlapudi, V. (1999). EGF- and NGF-stimulated translocation of cytohesin-1 to the plasma membrane of PC12 cells requires PI 3-kinase activation and a functional cytohesin-1 PH domain. Journal of Cell Science, 112
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25107
Oatey, P., Venkateswarlu, K., Williams, A., Fletcher, L., Foulstone, E., Cullen, P., Tavare, J., & Kanamarlapudi, V. (1999). Confocal imaging of the subcellular distribution of phosphatidylinositol 3,4,5-trisphosphate in insulin- and PDGF-stimulated 3T3-L1 adipocytes. Biochemical Journal, 344(2), 511
https://doi.org/10.1042/0264-6021:3440511, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25108
Cullen, P., Venkateswarlu, K., & Kanamarlapudi, V. (1999). Potential regulation of ADP-ribosylation factor 6 signalling by phosphatidylinositol 3,4,5-trisphosphate. Biochemical Society Transactions, 27(4), 683-689.
https://doi.org/10.1042/bst0270683, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52038
Kanamarlapudi, V. (1999). Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1.. The Biochemical Journal, 340, 359-363.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52037
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1220257/
VENKATESWARLU, K., GUNN-MOORE, F., OATEY, P., TAVARÉ, J., CULLEN, P., & Kanamarlapudi, V. (1998). Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain. Biochemical Journal, 335(1), 139-146.
https://doi.org/10.1042/bj3350139, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52039
Venkateswarlu, K., Lamb, D., Kelly, D., Manning, N., Kelly, S., & Kanamarlapudi, V. (1998). The N-Terminal Membrane Domain of Yeast NADPH-Cytochrome P450 (CYP) Oxidoreductase Is Not Required for Catalytic Activity in Sterol Biosynthesis or in Reconstitution of CYP Activity. Journal of Biological Chemistry, 273(8), 4492-4496.
https://doi.org/10.1074/jbc.273.8.4492, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25109
Venkateswarlu, K., Gunn-Moore, F., Oatey, P., Tavare, J., Cullen, P., & Kanamarlapudi, V. (1998). Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP ribosylation factor exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain. Biochemical Journal, 335
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25110
Venkateswarlu, K., Kelly, D., Manning, N., Kelly, S., & Kanamarlapudi, V. (1998). NADPH cytochrome P-450 oxidoreductase and susceptibility to ketoconazole. Antimicrobial Agents and Chemotherapy, 42
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25111
Venkateswarlu, K., Oatey, P., Tavare, J., Cullen, P., & Kanamarlapudi, V. (1998). Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase. Current Biology, 8(8), 463-466.
https://doi.org/10.1016/s0960-9822(98)70181-2, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25112
Cullen, P., Lockyer, P., Reynolds, J., Venkateswarlu, K., & Kanamarlapudi, V. (1997). GAP1IP4BP; a protein linking inositol 1,3,4,5-tetrakisphosphate with Ras and Ca2+homeostasis. Biochemical Society Transactions, 25(3), 507S.3-507S.
https://doi.org/10.1042/bst025507sb, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52041
Venkateswarlu, K., Kelly, S., & Kanamarlapudi, V. (1997). Stereoselective interaction of SCH 39304, a triazole, with sterol 14alpha-demethylase of Aspergillus fumigatus. Journal of Antimicrobial Chemotherapy, 39(5), 597-601.
https://doi.org/10.1093/jac/39.5.597, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25113
Denning, D., Venkateswarlu, K., Oakley, K., Anderson, M., Manning, N., Stevens, D., Warnock, D., Kelly, S., & Kanamarlapudi, V. (1997). Itraconazole resistance in Aspergillus fumigatus. Antimicrobial Agents and Chemotherapy, 41
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25114
Venkateswarlu, K., Denning, D., Kelly, S., & Kanamarlapudi, V. (1997). Inhibition and interaction of cytochrome P450 of Candida krusei with azole antifungal drugs. Journal of Medical and Veterinary Mycology, 35
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25115
Venkateswarlu, K., Denning, D., Kelly, S., & Kanamarlapudi, V. (1997). In-vitro activity of D0870, a new triazole antifungal drug, in comparison with fluconazole and itraconazole against Aspergillus fumigatus and Candida krusei. Journal of Antimicrobial Chemotherapy, 39(6), 731-736.
https://doi.org/10.1093/jac/39.6.731, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25116
Venkateswarlu, K., Taylor, M., Manning, N., Rinaldi, M., Kelly, S., & Kanamarlapudi, V. (1997). Fluconazole tolerance in clinical isolates of Cryptococcus neoformans. Antimicrobial Agents and Chemotherapy, 41
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25117
Lockyer, P., Bottomley, J., Reynolds, J., McNulty, T., Venkateswarlu, K., Potter, B., Dempsey, C., Cullen, P., & Kanamarlapudi, V. (1997). Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1IP4BP and GAP1m result from the GAP1IP4BP PH domain directing plasma membrane targeting. Current Biology, 7(12), 1007-1010.
https://doi.org/10.1016/s0960-9822(06)00423-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25118
Venkateswarlu, K., Kelly, D., Kelly, S., & Kanamarlapudi, V. (1997). Characterization of Saccharomyces cerevisiae CYP51 and a CYP51 fusion protein with NADPH cytochrome P-450 oxidoreductase expressed in Escherichia coli. Antimicrobial Agents and Chemotherapy, 41
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25119
Venkateswarlu, K., Kelly, S., & Kanamarlapudi, V. (1996). Biochemical characterisation of ketoconazole inhibitory action onAspergillus fumigatus. FEMS Immunology & Medical Microbiology, 16(1), 11-20.
https://doi.org/10.1111/j.1574-695X.1996.tb00106.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52042
Venkateswarlu, K., Denning, D., Manning, N., Kelly, S., & Kanamarlapudi, V. (1996). Reduced accumulation of drug in Candida krusei accounts for itraconazole resistance. Antimicrobial Agents and Chemotherapy, 40
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25120
Venkateswarlu, K., Marsh, R., Faber, B., Kelly, S., & Kanamarlapudi, V. (1996). Investigation of Cytochrome P450 Mediated Benzo(a)pyrene Hydroxylation in Aspergillus fumigatus. Journal of Chemical Technology & Biotechnology, 66(2), 139-144.
https://doi.org/10.1002/(sici)1097-4660(199606)66:2<139::aid-jctb480>3.3.co;2-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25121
Masaphy, S., Levanon, D., Henis, Y., Venkateswarlu, K., Kelly, S., & Kanamarlapudi, V. (1996). Evidence for cytochrome P-450 and P-450-mediated benzo(a) pyrene hydroxylation in the white rot fungusPhanerochaete chrysosporium. FEMS Microbiology Letters, 135(1), 51-55.
https://doi.org/10.1111/j.1574-6968.1996.tb07965.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25122
Venkateswarlu, K., Denning, D., Manning, N., Kelly, S., & Kanamarlapudi, V. (1996). Comparison of D0870, a new triazole antifungal agent, to fluconazole for inhibition of Candida albicans cytochrome P-450 by using in vitro assays. Antimicrobial Agents and Chemotherapy, 40
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25123
Venkateswarlu, K., Kelly, S., & Kanamarlapudi, V. (1996). Biochemical characterisation of ketoconazole inhibitory action onAspergillus fumigatus. FEMS Immunology & Medical Microbiology, 16(1), 11-20.
https://doi.org/10.1111/j.1574-695X.1996.tb00106.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25124
Masaphy, S. & Kanamarlapudi, V. (1996). Evidence for cytochrome P-450 and P-450-mediated benzo(a) pyrene hydroxylation in the white rot fungus Phanerochaete chrysosporium. FEMS Microbiology Letters, 135(1), 51-55.
https://doi.org/10.1016/0378-1097(95)00428-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52044
Venkateswarlu, K. & Kanamarlapudi, V. (1995). Resistance to fluconazole in Candida albicans from AIDS patients correlated with reduced intracellular accumulation of drug. FEMS Microbiology Letters, 131(3), 337-341.
https://doi.org/10.1016/0378-1097(95)00282-A, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52045
Venkateswarlu, K., Denning, D., Manning, N., Kelly, S., & Kanamarlapudi, V. (1995). Resistance to fluconazole inCandida albicansfrom AIDS patients correlated with reduced intracellular accumulation of drug. FEMS Microbiology Letters, 131(3), 337-341.
https://doi.org/10.1111/j.1574-6968.1995.tb07797.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25125
Masaphy, S., Levanon, D., Henis, Y., Venkateswarlu, K., Kelly, S., & Kanamarlapudi, V. (1995). Microsomal and cytosolic cytochrome P450 mediated benzo(a)pyrene hydroxylation in Pleurotus pulmonarius. Biotechnology Letters, 17(9), 969-974.
https://doi.org/10.1007/bf00127436, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25126
Fang, G., Venkateswarlu, K., Kelly, D., Kelly, S., & Kanamarlapudi, V. (1994). STUDIES ON YEAST HOST STRAINS FOR HETEROLOGOUS P450 EXPRESSION. Biotechnology Letters, 16
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25127
Padidam, M., Venkateswarlu, K., Johri, M., & Kanamarlapudi, V. (1991). Ammonium represses NADPH-nitrate reductase in the moss Funaria hygrometrica. Plant Science, 75(2), 185-194.
https://doi.org/10.1016/0168-9452(91)90233-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25128
VENKATESWARLU, K., POOLE, A., & Kanamarlapudi, V. (n.d.) SCREENING METHOD FOR REGULATORY ENZYMES EMPLOYING TRIBRID (TRI-HYBRID) SYSTEM
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26973
http://europepmc.org/patents/pat/WO03102221
Jannoo, R., Walker, W., & Kanamarlapudi, V. (2023). Targeting and Sensitization of Breast Cancer Cells to Killing with a Novel Interleukin-13 Receptor α2-Specific Hybrid Cytolytic Peptide. Cancers, 15(10), 2772
https://doi.org/10.3390/cancers15102772, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63511
http://dx.doi.org/10.3390/cancers15102772
Duckworth, E., Mortimer, M., Al‐Sarireh, B., Kanamarlapudi, V., & Roy, D. (2023). Frontline clinical diagnosis—FTIR on pancreatic cancer. Cancer Medicine, 12(16), 17340-17345.
https://doi.org/10.1002/cam4.6346, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65016
http://dx.doi.org/10.1002/cam4.6346
Reed, J., Higginbotham, V., Bain, S., & Kanamarlapudi, V. (2024). Comparative Analysis of Orthosteric and Allosteric GLP-1R Agonists’ Effects on Insulin Secretion from Healthy, Diabetic, and Recovered INS-1E Pancreatic Beta Cells. International Journal of Molecular Sciences, 25(12), 6331
https://doi.org/10.3390/ijms25126331, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa66723
Sargent, C., Ali, S., & Kanamarlapudi, V. (2024). The Evolution and Complications of Long-Term Mechanical Circulatory Support Devices. Hearts, 5(1), 105-121.
https://doi.org/10.3390/hearts5010008, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa66726
Reed, J., Bain, S., & Kanamarlapudi, V. (2024). The Regulation of Metabolic Homeostasis by Incretins and the Metabolic Hormones Produced by Pancreatic Islets. Diabetes, Metabolic Syndrome and Obesity, 17, 2419-2456.
https://doi.org/10.2147/dmso.s415934, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa66737
Short, E., (ICCARP), ., Adcock, I., Al-Sarireh, B., Ager, A., Ajjan, R., Akbar, N., Akeroyd, M., Alsaleh, G., Al-Sharbatee, G., Alavian, K., Amoaku, W., Andersen, J., Antoniades, C., Arends, M., Astley, S., Atan, D., Attanoos, R., Attems, J...., & Tree, J. (2024). Defining an ageing-related pathology, disease or syndrome: International Consensus Statement. GeroScience, 0
https://doi.org/10.1007/s11357-024-01315-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa67686

All Research

Journal Articles

Short, E., (ICCARP), ., Adcock, I., Al-Sarireh, B., Ager, A., Ajjan, R., Akbar, N., Akeroyd, M., Alsaleh, G., Al-Sharbatee, G., Alavian, K., Amoaku, W., Andersen, J., Antoniades, C., Arends, M., Astley, S., Atan, D., Attanoos, R., Attems, J...., & Tree, J. (2024). Defining an ageing-related pathology, disease or syndrome: International Consensus Statement. GeroScience, 0
https://doi.org/10.1007/s11357-024-01315-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa67686
Reed, J., Bain, S., & Kanamarlapudi, V. (2024). The Regulation of Metabolic Homeostasis by Incretins and the Metabolic Hormones Produced by Pancreatic Islets. Diabetes, Metabolic Syndrome and Obesity, 17, 2419-2456.
https://doi.org/10.2147/dmso.s415934, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa66737
Reed, J., Higginbotham, V., Bain, S., & Kanamarlapudi, V. (2024). Comparative Analysis of Orthosteric and Allosteric GLP-1R Agonists’ Effects on Insulin Secretion from Healthy, Diabetic, and Recovered INS-1E Pancreatic Beta Cells. International Journal of Molecular Sciences, 25(12), 6331
https://doi.org/10.3390/ijms25126331, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa66723
Sargent, C., Ali, S., & Kanamarlapudi, V. (2024). The Evolution and Complications of Long-Term Mechanical Circulatory Support Devices. Hearts, 5(1), 105-121.
https://doi.org/10.3390/hearts5010008, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa66726
Duckworth, E., Mortimer, M., Al‐Sarireh, B., Kanamarlapudi, V., & Roy, D. (2023). Frontline clinical diagnosis—FTIR on pancreatic cancer. Cancer Medicine, 12(16), 17340-17345.
https://doi.org/10.1002/cam4.6346, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65016
http://dx.doi.org/10.1002/cam4.6346
Jannoo, R., Walker, W., & Kanamarlapudi, V. (2023). Targeting and Sensitization of Breast Cancer Cells to Killing with a Novel Interleukin-13 Receptor α2-Specific Hybrid Cytolytic Peptide. Cancers, 15(10), 2772
https://doi.org/10.3390/cancers15102772, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63511
http://dx.doi.org/10.3390/cancers15102772
Guo, Y. & Kanamarlapudi, V. (2023). Molecular Analysis of SARS-CoV-2 Spike Protein-Induced Endothelial Cell Permeability and vWF Secretion. International Journal of Molecular Sciences, 24(6), 5664
https://doi.org/10.3390/ijms24065664, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63098
http://dx.doi.org/10.3390/ijms24065664
Row, P., Jannoo, R., Xia, Z., Row, P., & Kanamarlapudi, V. (2023). Targeting of the Interleukin-13 Receptor (IL-13R)α2 Expressing Prostate Cancer by a Novel Hybrid Lytic Peptide. Biomolecules, 13(2), 356
https://doi.org/10.3390/biom13020356, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63097
http://dx.doi.org/10.3390/biom13020356
Kanamarlapudi, V., Tamaddon Jahromi, S., & Murphy, K. (2022). ADP-ribosylation factor 6 expression increase in oesophageal adenocarcinoma suggests a potential biomarker role for it. PLOS ONE, 17(2), e0263845
https://doi.org/10.1371/journal.pone.0263845, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60111
Reed, J., Bain, S., & Kanamarlapudi, V. (2021). A Review of Current Trends with Type 2 Diabetes Epidemiology, Aetiology, Pathogenesis, Treatments and Future Perspectives. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 14, 3567-3602.
https://doi.org/10.2147/dmso.s319895, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57318
Francis, W., Owens, S., Kanamarlapudi, V., & Xia, Z. (2021). Role of hypoxia inducible factor 1alpha in cobalt nanoparticle induced cytotoxicity of human THP-1 macrophages. Biomaterials Translational, 2(2), 143-150.
https://doi.org/10.12336/biomatertransl.2021.02.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57975
Sargent, C., Perkins, I., Kanamarlapudi, V., Moriarty, C., & Ali, S. (2021). Hemodilution Increases the Susceptibility of Red Blood Cells to Mechanical Shear Stress During In Vitro Hemolysis Testing. ASAIO Journal, 67(6), 632-641.
https://doi.org/10.1097/mat.0000000000001280, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57577
Reed, J., Bain, S., & Kanamarlapudi, V. (2020). Recent advances in understanding the role of glucagon-like peptide 1. F1000Research, 9, 239
https://doi.org/10.12688/f1000research.20602.1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54102
Chiou, T., Long, P., Schumann-Gillett, A., Kanamarlapudi, V., Haas, S., Harvey, K., O’Mara, M., Blas, A., Kalscheuer, V., & Harvey, R. (2019). Mutation p.R356Q in the Collybistin Phosphoinositide Binding Site Is Associated With Mild Intellectual Disability. Frontiers in Molecular Neuroscience, 12
https://doi.org/10.3389/fnmol.2019.00060, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50064
Eva, R., Koseki, H., Kanamarlapudi, V., & Fawcett, J. (2017). EFA6 regulates selective polarised transport and axon regeneration from the axon initial segment. Journal of Cell Science, 130(21), 3663-3675.
https://doi.org/10.1242/jcs.207423, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35637
John, D., Williams, L., Kanamarlapudi, V., Humphrey, T., & Wilkinson, T. (2017). The Bacterial Species Campylobacter jejuni Induce Diverse Innate Immune Responses in Human and Avian Intestinal Epithelial Cells. Frontiers in Microbiology, 8
https://doi.org/10.3389/fmicb.2017.01840, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35842
Chan, C., Pieper, I., Robinson, C., Friedmann, Y., Kanamarlapudi, V., & Thornton, C. (2017). Shear Stress-Induced Total Blood Trauma in Multiple Species. Artificial Organs
https://doi.org/10.1111/aor.12932, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31746
Thornton, C., Cronin, J., Kanamarlapudi, V., & Sheldon, M. (2016). Signal transducer and activator of transcription-3 licenses Toll-like receptor 4-dependent interleukin (IL)-6 and IL-8 production via IL-6 receptor-positive feedback in endometrial cells. Mucosal Immunology, 9(4), 1125-1136.
https://doi.org/10.1038/mi.2015.131, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25017
http://www.nature.com/mi/journal/vaop/ncurrent/full/mi2015131a.html
Thompson, A., Stephens, J., Bain, S., & Kanamarlapudi, V. (2016). Molecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor Internalisation. PLOS ONE, 11(4), e0154229
https://doi.org/10.1371/journal.pone.0154229, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27352
Venkateswarlu, K., Uma, D., Andrés, L., & Kanamarlapudi, V. (2016). Luteinizing hormone/chorionic gonadotrophin receptor overexpressed in granulosa cells from polycystic ovary syndrome ovaries is functionally active. Reproductive BioMedicine Online
https://doi.org/10.1016/j.rbmo.2016.03.003, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26971
Thompson, A. & Kanamarlapudi, V. (2015). Distinct Regions in the C-Terminus Required for GLP-1R Cell Surface Expression, Activity and Internalisation. Molecular and Cellular Endocrinology, 413, 66-77.
https://doi.org/10.1016/j.mce.2015.06.012, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa22217
Franssen, E., Zhao, R., Koseki, H., Kanamarlapudi, V., Hoogenraad, C., Eva, R., Fawcett, J., & Kanamarlapudi, V. (2015). Exclusion of Integrins from CNS Axons Is Regulated by Arf6 Activation and the AIS. Journal of Neuroscience, 35(21), 8359-8375.
https://doi.org/10.1523/JNEUROSCI.2850-14.2015, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa21767
Thompson, A. & Kanamarlapudi, V. (2015). Agonist-induced internalisation of the glucagon-like peptide-1 receptor is mediated by the Gαq pathway. Biochemical Pharmacology, 93(1), 72-84.
https://doi.org/10.1016/j.bcp.2014.10.015, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19150
Chan, C., Pieper, I., Fleming, S., Friedmann, Y., Foster, G., Hawkins, K., Thornton, C., & Kanamarlapudi, V. (2014). The Effect of Shear Stress on the Size, Structure, and Function of Human von Willebrand Factor. Artificial Organs, 38(9), 741-750.
https://doi.org/10.1111/aor.12382, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18740
Thompson, A. & Kanamarlapudi, V. (2014). The regions within the N-terminus critical for human glucagon like peptide-1 receptor (hGLP-1R) cell Surface expression. Scientific Reports, 4, 7410
https://doi.org/10.1038/srep07410, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19782
Davies, J., Tamaddon-Jahromi, S., Jannoo, R., & Kanamarlapudi, V. (2014). Cytohesin 2/ARF6 regulates preadipocyte migration through the activation of ERK1/2. Biochemical Pharmacology, 92(4), 651-660.
https://doi.org/10.1016/j.bcp.2014.09.023, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18768
Konstantinou, D., Lei, M., Xia, Z., & Kanamarlapudi, V. (2014). Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor. Cell Biology International, 39(4), 502-507.
https://doi.org/10.1002/cbin.10409, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19760
Kanamarlapudi, V. & Kanamarlapudi, V. (2014). Exchange factor EFA6R requires C-terminal targeting to the plasma membrane to promote cytoskeletal rearrangement through the activation of ARF6. Journal of Biological Chemistry, 289(48), 33378-33390.
https://doi.org/10.1074/jbc.M113.534156, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18668
Francis, W., Owens, S., Xia, Z., & Kanamarlapudi, V. (2014). The temporal expression of estrogen receptor alpha-36 and runx2 in human bone marrow derived mesenchymal stromal cells during osteogenesis. Biochem Biophys Res Commun
https://doi.org/10.1016/j.bbrc.2014.09.111, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19126
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=25281901
Davies, J., Bain, S., & Kanamarlapudi, V. (2014). ADP-ribosylation factor 6 regulates endothelin-1-induced lipolysis in adipocytes. BIOCHEMICAL PHARMACOLOGY, 90(4), 406-413.
https://doi.org/10.1016/j.bcp.2014.06.012, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18415
Tu, Y., Xue, H., Francis, W., Davies, A., Pallister, I., Kanamarlapudi, V., & Xia, Z. (2013). Lactoferrin inhibits dexamethasone-induced chondrocyte impairment from osteoarthritic cartilage through up-regulation of extracellular signal-regulated kinase 1/2 and suppression of FASL, FAS, and Caspase 3. Biochemical and Biophysical Research Communications, 441(1), 249-255.
https://doi.org/10.1016/j.bbrc.2013.10.047, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16395
Aiysha Thompson, K. & Kanamarlapudi, V. (2013). Type 2 Diabetes Mellitus and Glucagon Like Peptide-1 Receptor Signalling. Clinical & Experimental Pharmacology, 03(04)
https://doi.org/10.4172/2161-1459.1000138, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27395
Kanamarlapudi, V., Owens, S., Saha, K., Pope, R., & Mundell, S. (2012). ARF6-Dependent Regulation of P2Y Receptor Traffic and Function in Human Platelets. PLoS ONE, 7(8), e43532
https://doi.org/10.1371/journal.pone.0043532, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12399
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0043532
Eva, R., Crisp, S., Marland, J., Norman, J., Kanamarlapudi, V., ffrench-Constant, C., & Fawcett, J. (2012). ARF6 Directs Axon Transport and Traffic of Integrins and Regulates Axon Growth in Adult DRG Neurons. The Journal of Neuroscience, 32(30), 10352-10364.
https://doi.org/10.1523/JNEUROSCI.1409-12.2012, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12274
Kanamarlapudi, V., Owens, S., Lartey, J., & Bernal, A. (2012). ADP-Ribosylation Factor 6 Expression and Activation Are Reduced in Myometrium in Complicated Pregnancies. PLoS ONE, 7(5), e37954
https://doi.org/10.1371/journal.pone.0037954, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa11278
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0037954
Kanamarlapudi, V., Thompson, A., Kelly, E., & Bernal, A. (2012). ARF6 Activated by the LHCG Receptor through the Cytohesin Family of Guanine Nucleotide Exchange Factors Mediates the Receptor Internalization and Signaling. Journal of Biological Chemistry, 287(24), 20443
https://doi.org/10.1074/jbc.M112.362087, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa11277
Kalscheuer, V., Musante, L., Fang, C., Hoffmann, K., Fuchs, C., Carta, E., Deas, E., Venkateswarlu, K., Menzel, C., Ullmann, R., Tommerup, N., Dalprà, L., Tzschach, A., Selicorni, A., Lüscher, B., Ropers, H., Harvey, K., Harvey, R., & Kanamarlapudi, V. (2009). A balanced chromosomal translocation disrupting ARHGEF9 is associated with epilepsy, anxiety, aggression, and mental retardation. Human Mutation, 30(1), 61-68.
https://doi.org/10.1002/humu.20814, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10516
Stewart, R., Song, L., Carter, S., Sigalas, C., Zaccai, N., Kanamarlapudi, V., Bhat, M., Takeshima, H., & Sitsapesan, R. (2008). Single-Channel Characterization of the Rabbit Recombinant RyR2 Reveals a Novel Inactivation Property of Physiological Concentrations of ATP. Journal of Membrane Biology, 222(2), 65-77.
https://doi.org/10.1007/s00232-008-9102-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10515
Venkateswarlu, K., Brandom, K., Yun, H., & Kanamarlapudi, V. (2007). PI-3-kinase-dependent membrane recruitment of centaurin- 2 is essential for its effect on ARF6-mediated actin cytoskeleton reorganisation. Journal of Cell Science, 120(5), 792-801.
https://doi.org/10.1242/jcs.03373, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1354
Bouschet, T., Martin, S., Kanamarlapudi, V., Mundell, S., & Henley, J. (2007). The calcium-sensing receptor changes cell shape via a beta-arrestin-1 ARNO ARF6 ELMO protein network. Journal of Cell Science, 120(15), 2489-2497.
https://doi.org/10.1242/jcs.03469, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25090
Kanumilli, S., Tringham, E., Payne, C., Dupere, J., Venkateswarlu, K., Usowicz, M., & Kanamarlapudi, V. (2006). Alternative splicing generates a smaller assortment of CaV2.1 transcripts in cerebellar Purkinje cells than in the cerebellum. Physiological Genomics, 24(2), 86-96.
https://doi.org/10.1152/physiolgenomics.00149.2005, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25091
Lawrence, J., Mundell, S., Yun, H., Kelly, E., Venkateswarlu, K., & Kanamarlapudi, V. (2005). Centaurin- 1, an ADP-Ribosylation Factor 6 GTPase Activating Protein, Inhibits 2-Adrenoceptor Internalization. Molecular Pharmacology, 67(6), 1822-1828.
https://doi.org/10.1124/mol.105.011338, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25092
Kanamarlapudi, V. & Kanamarlapudi, V. (2005). Centaurin-alpha(1) and KIF13B kinesin motor protein interaction in ARF6 signalling. Biochemical Society Transactions, 33
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25093
Gunn-Moore, F., Welsh, G., Herron, L., Brannigan, F., Venkateswarlu, K., Gillespie, S., Brandwein-Gensler, M., Madan, R., Tavare, J., Brophy, P., Prystowsky, M., Guild, S., & Kanamarlapudi, V. (2005). A novel 4.1 ezrin radixin moesin (FERM)-containing protein, ‘Willin’. FEBS Letters, 579(22), 5089-5094.
https://doi.org/10.1016/j.febslet.2005.07.097, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25095
Kanamarlapudi, V. & Kanamarlapudi, V. (2005). Centaurin-α1 and KIF13B kinesin motor protein interaction in ARF6 signalling. Biochemical Society Transactions, 33(6), 1279
https://doi.org/10.1042/BST20051279, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26972
http://europepmc.org/abstract/med/16246098
Venkateswarlu, K. & Kanamarlapudi, V. (2005). Centaurin- 1 interacts directly with kinesin motor protein KIF13B. Journal of Cell Science, 118(11), 2471-2484.
https://doi.org/10.1242/jcs.02369, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1355
Lockyer, P., Bottomley, J., Reynolds, J., McNulty, T., Venkateswarlu, K., Potter, B., Dempsey, C., Cullen, P., & Kanamarlapudi, V. (2004). Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1 IP4BP and GAP1 m result from the GAP1 IP4BP PH domain directing plasma membrane targeting. Current Biology, 7(12), 1007-1010.
https://doi.org/10.1016/S0960-9822(06)00423-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52040
Venkateswarlu, K. & Kanamarlapudi, V. (2003). Centaurin- 1 Is an in Vivo Phosphatidylinositol 3,4,5-Trisphosphate-dependent GTPase-activating Protein for ARF6 That Is Involved in Actin Cytoskeleton Organization. Journal of Biological Chemistry, 279(8), 6205-6208.
https://doi.org/10.1074/jbc.C300482200, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1356
Venkateswarlu, K. & Kanamarlapudi, V. (2003). Interaction Protein for Cytohesin Exchange Factors 1 (IPCEF1) Binds Cytohesin 2 and Modifies Its Activity. Journal of Biological Chemistry, 278(44), 43460-43469.
https://doi.org/10.1074/jbc.M304078200, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1357
Kanumilli, S., Toms, N., Venkateswarlu, K., Mellor, H., Roberts, P., & Kanamarlapudi, V. (2002). Functional coupling of rat metabotropic glutamate 1a receptors to phospholipase D in CHO cells: involvement of extracellular Ca2+, protein kinase C, tyrosine kinase and Rho-A. Neuropharmacology, 42(1), 1-8.
https://doi.org/10.1016/s0028-3908(01)00161-7, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25096
Bobe, R., Wilde, J., Maschberger, P., Venkateswarlu, K., Cullen, P., Siess, W., Watson, S., & Kanamarlapudi, V. (2001). Phosphatidylinositol 3-kinase-dependent translocation of phospholipase Cgamma2 in mouse megakaryocytes is independent of Bruton tyrosine kinase translocation. Blood, 97(3), 678-684.
https://doi.org/10.1182/blood.V97.3.678, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25097
Lamb, D., Kaderbhai, N., Venkateswarlu, K., Kelly, D., Kelly, S., Kaderbhai, M., & Kanamarlapudi, V. (2001). Human Sterol 14α-Demethylase Activity Is Enhanced by the Membrane-Bound State of Cytochrome b5. Archives of Biochemistry and Biophysics, 395(1), 78-84.
https://doi.org/10.1006/abbi.2001.2566, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25098
Dubois, T., Kerai, P., Zemlickova, E., Howell, S., Jackson, T., Venkateswarlu, K., Cullen, P., Theibert, A., Larose, L., Roach, P., Aitken, A., & Kanamarlapudi, V. (2001). Casein Kinase I Associates with Members of the Centaurin-alpha Family of Phosphatidylinositol 3,4,5-Trisphosphate-binding Proteins. Journal of Biological Chemistry, 276(22), 18757-18764.
https://doi.org/10.1074/jbc.M010005200, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25099
Lamb, D., Warrilow, A., Venkateswarlu, K., Kelly, D., Kelly, S., & Kanamarlapudi, V. (2001). Activities and Kinetic Mechanisms of Native and Soluble NADPH–Cytochrome P450 Reductase. Biochemical and Biophysical Research Communications, 286(1), 48-54.
https://doi.org/10.1006/bbrc.2001.5338, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25100
Venkateswarlu, K., Cullen, P., & Kanamarlapudi, V. (2000). Signalling via ADP-ribosylation factor 6 lies downstream of phosphatidylinositide 3-kinase. Biochemical Journal, 345(3), 719
https://doi.org/10.1042/0264-6021:3450719, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25101
Cullen, P., Venkateswarlu, K., & Kanamarlapudi, V. (1999). Potential regulation of ADP-ribosylation factor 6 signalling by phosphatidylinositol 3,4,5-trisphosphaee. Biochemical Society Transactions, 27
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25102
Venkateswarlu, K., Cullen, P., & Kanamarlapudi, V. (1999). Molecular Cloning and Functional Characterization of a Human Homologue of Centaurin-α. Biochemical and Biophysical Research Communications, 262(1), 237-244.
https://doi.org/10.1006/bbrc.1999.1065, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25103
Lockyer, P., Wennstrom, S., Kupzig, S., Venkateswarlu, K., Downward, J., Cullen, P., & Kanamarlapudi, V. (1999). Identification of the Ras GTPase-activating protein GAP1m as a phosphatidylinositol-3,4,5-trisphosphate-binding protein in vivo. Current Biology, 9(5), 265-269.
https://doi.org/10.1016/s0960-9822(99)80116-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25104
Venkateswarlu, K., Oatey, P., Tavare, J., Jackson, T., Cullen, P., & Kanamarlapudi, V. (1999). Identification of centaurin-α1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1. Biochemical Journal, 340(2), 359
https://doi.org/10.1042/0264-6021:3400359, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25105
Lamb, D., Kelly, D., Venkateswarlu, K., Manning, N., Bligh, H., Schunck, W., Kelly, S., & Kanamarlapudi, V. (1999). Generation of a Complete, Soluble, and Catalytically Active Sterol 14α-Demethylase−Reductase Complex†. Biochemistry, 38(27), 8733-8738.
https://doi.org/10.1021/bi9825089, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25106
Venkateswarlu, K., Gunn-Moore, F., Tavare, J., Cullen, P., & Kanamarlapudi, V. (1999). EGF- and NGF-stimulated translocation of cytohesin-1 to the plasma membrane of PC12 cells requires PI 3-kinase activation and a functional cytohesin-1 PH domain. Journal of Cell Science, 112
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25107
Oatey, P., Venkateswarlu, K., Williams, A., Fletcher, L., Foulstone, E., Cullen, P., Tavare, J., & Kanamarlapudi, V. (1999). Confocal imaging of the subcellular distribution of phosphatidylinositol 3,4,5-trisphosphate in insulin- and PDGF-stimulated 3T3-L1 adipocytes. Biochemical Journal, 344(2), 511
https://doi.org/10.1042/0264-6021:3440511, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25108
Cullen, P., Venkateswarlu, K., & Kanamarlapudi, V. (1999). Potential regulation of ADP-ribosylation factor 6 signalling by phosphatidylinositol 3,4,5-trisphosphate. Biochemical Society Transactions, 27(4), 683-689.
https://doi.org/10.1042/bst0270683, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52038
Kanamarlapudi, V. (1999). Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1.. The Biochemical Journal, 340, 359-363.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52037
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1220257/
VENKATESWARLU, K., GUNN-MOORE, F., OATEY, P., TAVARÉ, J., CULLEN, P., & Kanamarlapudi, V. (1998). Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain. Biochemical Journal, 335(1), 139-146.
https://doi.org/10.1042/bj3350139, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52039
Venkateswarlu, K., Lamb, D., Kelly, D., Manning, N., Kelly, S., & Kanamarlapudi, V. (1998). The N-Terminal Membrane Domain of Yeast NADPH-Cytochrome P450 (CYP) Oxidoreductase Is Not Required for Catalytic Activity in Sterol Biosynthesis or in Reconstitution of CYP Activity. Journal of Biological Chemistry, 273(8), 4492-4496.
https://doi.org/10.1074/jbc.273.8.4492, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25109
Venkateswarlu, K., Gunn-Moore, F., Oatey, P., Tavare, J., Cullen, P., & Kanamarlapudi, V. (1998). Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP ribosylation factor exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain. Biochemical Journal, 335
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25110
Venkateswarlu, K., Kelly, D., Manning, N., Kelly, S., & Kanamarlapudi, V. (1998). NADPH cytochrome P-450 oxidoreductase and susceptibility to ketoconazole. Antimicrobial Agents and Chemotherapy, 42
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25111
Venkateswarlu, K., Oatey, P., Tavare, J., Cullen, P., & Kanamarlapudi, V. (1998). Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase. Current Biology, 8(8), 463-466.
https://doi.org/10.1016/s0960-9822(98)70181-2, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25112
Cullen, P., Lockyer, P., Reynolds, J., Venkateswarlu, K., & Kanamarlapudi, V. (1997). GAP1IP4BP; a protein linking inositol 1,3,4,5-tetrakisphosphate with Ras and Ca2+homeostasis. Biochemical Society Transactions, 25(3), 507S.3-507S.
https://doi.org/10.1042/bst025507sb, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52041
Venkateswarlu, K., Kelly, S., & Kanamarlapudi, V. (1997). Stereoselective interaction of SCH 39304, a triazole, with sterol 14alpha-demethylase of Aspergillus fumigatus. Journal of Antimicrobial Chemotherapy, 39(5), 597-601.
https://doi.org/10.1093/jac/39.5.597, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25113
Denning, D., Venkateswarlu, K., Oakley, K., Anderson, M., Manning, N., Stevens, D., Warnock, D., Kelly, S., & Kanamarlapudi, V. (1997). Itraconazole resistance in Aspergillus fumigatus. Antimicrobial Agents and Chemotherapy, 41
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25114
Venkateswarlu, K., Denning, D., Kelly, S., & Kanamarlapudi, V. (1997). Inhibition and interaction of cytochrome P450 of Candida krusei with azole antifungal drugs. Journal of Medical and Veterinary Mycology, 35
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25115
Venkateswarlu, K., Denning, D., Kelly, S., & Kanamarlapudi, V. (1997). In-vitro activity of D0870, a new triazole antifungal drug, in comparison with fluconazole and itraconazole against Aspergillus fumigatus and Candida krusei. Journal of Antimicrobial Chemotherapy, 39(6), 731-736.
https://doi.org/10.1093/jac/39.6.731, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25116
Venkateswarlu, K., Taylor, M., Manning, N., Rinaldi, M., Kelly, S., & Kanamarlapudi, V. (1997). Fluconazole tolerance in clinical isolates of Cryptococcus neoformans. Antimicrobial Agents and Chemotherapy, 41
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25117
Lockyer, P., Bottomley, J., Reynolds, J., McNulty, T., Venkateswarlu, K., Potter, B., Dempsey, C., Cullen, P., & Kanamarlapudi, V. (1997). Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1IP4BP and GAP1m result from the GAP1IP4BP PH domain directing plasma membrane targeting. Current Biology, 7(12), 1007-1010.
https://doi.org/10.1016/s0960-9822(06)00423-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25118
Venkateswarlu, K., Kelly, D., Kelly, S., & Kanamarlapudi, V. (1997). Characterization of Saccharomyces cerevisiae CYP51 and a CYP51 fusion protein with NADPH cytochrome P-450 oxidoreductase expressed in Escherichia coli. Antimicrobial Agents and Chemotherapy, 41
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25119
Venkateswarlu, K., Kelly, S., & Kanamarlapudi, V. (1996). Biochemical characterisation of ketoconazole inhibitory action onAspergillus fumigatus. FEMS Immunology & Medical Microbiology, 16(1), 11-20.
https://doi.org/10.1111/j.1574-695X.1996.tb00106.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52042
Venkateswarlu, K., Denning, D., Manning, N., Kelly, S., & Kanamarlapudi, V. (1996). Reduced accumulation of drug in Candida krusei accounts for itraconazole resistance. Antimicrobial Agents and Chemotherapy, 40
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25120
Venkateswarlu, K., Marsh, R., Faber, B., Kelly, S., & Kanamarlapudi, V. (1996). Investigation of Cytochrome P450 Mediated Benzo(a)pyrene Hydroxylation in Aspergillus fumigatus. Journal of Chemical Technology & Biotechnology, 66(2), 139-144.
https://doi.org/10.1002/(sici)1097-4660(199606)66:2<139::aid-jctb480>3.3.co;2-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25121
Masaphy, S., Levanon, D., Henis, Y., Venkateswarlu, K., Kelly, S., & Kanamarlapudi, V. (1996). Evidence for cytochrome P-450 and P-450-mediated benzo(a) pyrene hydroxylation in the white rot fungusPhanerochaete chrysosporium. FEMS Microbiology Letters, 135(1), 51-55.
https://doi.org/10.1111/j.1574-6968.1996.tb07965.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25122
Venkateswarlu, K., Denning, D., Manning, N., Kelly, S., & Kanamarlapudi, V. (1996). Comparison of D0870, a new triazole antifungal agent, to fluconazole for inhibition of Candida albicans cytochrome P-450 by using in vitro assays. Antimicrobial Agents and Chemotherapy, 40
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25123
Venkateswarlu, K., Kelly, S., & Kanamarlapudi, V. (1996). Biochemical characterisation of ketoconazole inhibitory action onAspergillus fumigatus. FEMS Immunology & Medical Microbiology, 16(1), 11-20.
https://doi.org/10.1111/j.1574-695X.1996.tb00106.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25124
Masaphy, S. & Kanamarlapudi, V. (1996). Evidence for cytochrome P-450 and P-450-mediated benzo(a) pyrene hydroxylation in the white rot fungus Phanerochaete chrysosporium. FEMS Microbiology Letters, 135(1), 51-55.
https://doi.org/10.1016/0378-1097(95)00428-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52044
Venkateswarlu, K. & Kanamarlapudi, V. (1995). Resistance to fluconazole in Candida albicans from AIDS patients correlated with reduced intracellular accumulation of drug. FEMS Microbiology Letters, 131(3), 337-341.
https://doi.org/10.1016/0378-1097(95)00282-A, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52045
Venkateswarlu, K., Denning, D., Manning, N., Kelly, S., & Kanamarlapudi, V. (1995). Resistance to fluconazole inCandida albicansfrom AIDS patients correlated with reduced intracellular accumulation of drug. FEMS Microbiology Letters, 131(3), 337-341.
https://doi.org/10.1111/j.1574-6968.1995.tb07797.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25125
Masaphy, S., Levanon, D., Henis, Y., Venkateswarlu, K., Kelly, S., & Kanamarlapudi, V. (1995). Microsomal and cytosolic cytochrome P450 mediated benzo(a)pyrene hydroxylation in Pleurotus pulmonarius. Biotechnology Letters, 17(9), 969-974.
https://doi.org/10.1007/bf00127436, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25126
Fang, G., Venkateswarlu, K., Kelly, D., Kelly, S., & Kanamarlapudi, V. (1994). STUDIES ON YEAST HOST STRAINS FOR HETEROLOGOUS P450 EXPRESSION. Biotechnology Letters, 16
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25127
Padidam, M., Venkateswarlu, K., Johri, M., & Kanamarlapudi, V. (1991). Ammonium represses NADPH-nitrate reductase in the moss Funaria hygrometrica. Plant Science, 75(2), 185-194.
https://doi.org/10.1016/0168-9452(91)90233-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25128

Book Chapters

Venkateswarlu, K. & Kanamarlapudi, V. (2005). GTPases Regulating Membrane Dynamics. Analysis of the Interaction Between Cytohesin 2 and IPCEF1 (pp. 252-266).
https://doi.org/10.1016/s0076-6879(05)04024-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25094

Other Research Outputs

VENKATESWARLU, K., POOLE, A., & Kanamarlapudi, V. (n.d.) SCREENING METHOD FOR REGULATORY ENZYMES EMPLOYING TRIBRID (TRI-HYBRID) SYSTEM
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26973
http://europepmc.org/patents/pat/WO03102221

Supervision

Enhanced Osteogenesis by Combing Exogenous BMPs with Hydroxyapatite/Calcium Carbonate Bone Grafts: In Vitro and In Vivo Study (current)

MD

Other supervisor: Dr James Murray
Contemporary approaches to the diagnosis and management of Pancreatic Ductal Adenocarcinoma, examining the role of biomarkers in aiding early diagnosis (awarded 2024)

MD

Other supervisor: Dr William Walker

Other supervisor: Prof Peter Dunstan
Molecular Analysis of the Role of Shear and Glycosylation in von Willebrand Factor Degradation by ADAMTS13 (awarded 2024)

PhD

Other supervisor: Prof Karl Hawkins
Analysis of Mechanisms Involved in Ventricular Assist Device (VAD) Induced Extracellular Vesicles Generation and their Cellular Effects (awarded 2022)

PhD

Other supervisor: Prof Yuqin Wang
Molecular and Cellular Analysis of Endothelial Permeability in Sepsis (awarded 2024)

PhD

Other supervisor: Prof Thomas Wilkinson
Enhancing osteogenic capabilities of human umbilical cord matrix mesenchymal stem cells of 3D-printed hydroxyapatite/calcium carbonate scaffolds (awarded 2022)

MSc

Other supervisor: Dr Zhidao Xia

Taught Modules

PM-130 Fundamental Research Skills

This module is designed to develop the skills required for students of biochemistry and genetics degree programmes. Students meet with their tutors and will be given a series of assignments designed to develop skills in key areas such as essay writing, presentations and general numeracy.
PM-280 Skills for Researchers

The modern scientist graduate is expected to have gained extensive laboratory-based experience and this is certainly essential for any student intent on pursuing a research-based career. Skills for Researchers provides students with the opportunity to acquire the core skills to be able to conduct, analyse, interpret and present scientific experiments. A proportion of the module will be spent in the laboratory gaining hands-on experience. Skills acquired in this module will form the basis for future experimental work, including the final year project. Students will have the opportunity to provide feedback to peers and engage with a variety of online learning materials.
PM-331 Membrane Trafficking

The module provides an understanding of the subcellular organelles, the regulation of their biosynthesis and how impairment of this process leads to disease.
PM-340 Being a Medical Scientist

Much of a scientist¿s career is spent writing and speaking about science. The aim of this module is to give students a higher level experience of what being a lead researcher is like, away from the lab bench. Drawing on core knowledge from other modules, students will refine their oral and written communication and learn what leadership skills are needed to succeed in modern science. They will also be challenged to consider ethical aspects of research, including new technologies and the use of animal and human subjects. The module will be highly interactive, taught using informal lectures interspersed with students working in groups.
PM-344 Capstone Project

The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.
PM-376 Advanced Research Topics in Biomedical Science

This module seeks to highlight various research activity currently conducted within the Swansea University Medical School, providing students with an understanding of a diverse array of research topics investigated within the biomedical sciences. Topics covered will reflect the current research staff activity including the role of extracellular vesicles in cancer, cancer therapeutics, biomaterials, role of cholesterol in cell biology, and use of lipidomics. Students will gain a background to each topic, an appreciation of the current methodologies utilised within each field and the current research developments within these.
PMRM04 Dissertation (Research)

This module builds on the knowledge and skills developed in teaching components in part one of their relevant programme. Students will work independently in order to critically explore and add to the evidence base for a topic of relevance to their area of study.

Career History

Research Reader in Molecular Cell Biology and Pharmacology , Swansea University Medical School

May 2007 - September 2009
Lecturer in Cellular Pharmacology , School of Physiology and Pharmacology, The University of Bristol

October 2004 - April 2007
BBSRC David Phillips Research Fellowship and Proleptic Lecturer, School of Physiology and Pharmacology, The University of Bristol

October 1999 - September 2004
Postdoctoral Researcher , School of Biochemistry, The University of Bristol

October 1996 - September 1999
Research Scientist , AstraZeneca (India), Bangalore

February 1990 - September 1993

Professor Venkat Kanamarlapudi

Telephone number

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Research Highlights

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Other Research Outputs

Supervision

Enhanced Osteogenesis by Combing Exogenous BMPs with Hydroxyapatite/Calcium Carbonate Bone Grafts: In Vitro and In Vivo Study (current)

Contemporary approaches to the diagnosis and management of Pancreatic Ductal Adenocarcinoma, examining the role of biomarkers in aiding early diagnosis (awarded 2024)

Molecular Analysis of the Role of Shear and Glycosylation in von Willebrand Factor Degradation by ADAMTS13 (awarded 2024)

Analysis of Mechanisms Involved in Ventricular Assist Device (VAD) Induced Extracellular Vesicles Generation and their Cellular Effects (awarded 2022)

Molecular and Cellular Analysis of Endothelial Permeability in Sepsis (awarded 2024)

Enhancing osteogenic capabilities of human umbilical cord matrix mesenchymal stem cells of 3D-printed hydroxyapatite/calcium carbonate scaffolds (awarded 2022)

Taught Modules

PM-130 Fundamental Research Skills

PM-280 Skills for Researchers

PM-331 Membrane Trafficking

PM-340 Being a Medical Scientist

PM-344 Capstone Project

PM-376 Advanced Research Topics in Biomedical Science

PMRM04 Dissertation (Research)

Career History

Research Reader in Molecular Cell Biology and Pharmacology , Swansea University Medical School

Lecturer in Cellular Pharmacology , School of Physiology and Pharmacology, The University of Bristol

BBSRC David Phillips Research Fellowship and Proleptic Lecturer, School of Physiology and Pharmacology, The University of Bristol

Postdoctoral Researcher , School of Biochemistry, The University of Bristol

Research Scientist , AstraZeneca (India), Bangalore