Dr Matthew Hitchings

Research Highlights

1. Mageiros, L., Méric, G., Bayliss, S., Pensar, J., Pascoe, B., Mourkas, E., Calland, J., Yahara, K., Murray, S., Wilkinson, T., Williams, L., Hitchings, M., Porter, J., Kemmett, K., Feil, E., Jolley, K., Williams, N., Corander, J., Sheppard, S., & Hitchings, M. (2021). Genome evolution and the emergence of pathogenicity in avian Escherichia coli. Nature Communications, 12(1)

   https://doi.org/10.1038/s41467-021-20988-w, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56200

   http://dx.doi.org/10.1038/s41467-021-20988-w
2. Muñoz-Ramirez, Z., Pascoe, B., Mendez-Tenorio, A., Mourkas, E., Sandoval-Motta, S., Perez-Perez, G., Morgan, D., Dominguez, R., Ortiz-Princz, D., Cavazza, M., Rocha, G., Queiroz, D., Catalano, M., Palma, G., Goldman, C., Venegas, A., Alarcon, T., Oleastro, M., Vale, F...., & Torres, J. (2021). A 500-year tale of co-evolution, adaptation, and virulence: Helicobacter pylori in the Americas. The ISME Journal, 15(1), 78-92.

   https://doi.org/10.1038/s41396-020-00758-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56201
3. Calland, J., Pascoe, B., Bayliss, S., Mourkas, E., Berthenet, E., Thorpe, H., Hitchings, M., Feil, E., Corander, J., Blaser, M., Falush, D., & Sheppard, S. (2021). Quantifying bacterial evolution in the wild: A birthday problem for Campylobacter lineages. PLOS Genetics, 17(9), e1009829

   https://doi.org/10.1371/journal.pgen.1009829, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56204
4. Llewellyn, C., Greig, C., Silkina, A., Kultschar, B., Hitchings, M., & Farnham, G. (2020). Mycosporine-like amino acid and aromatic amino acid transcriptome response to UV and far-red light in the cyanobacterium Chlorogloeopsis fritschii PCC 6912. Scientific Reports, 10(1)

   https://doi.org/10.1038/s41598-020-77402-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55786
5. Brown, H., Metters, G., Hitchings, M., Wilkinson, T., Sousa, L., Cooper, J., Dance, H., Atterbury, R., & Jenkins, R. (2020). Antibacterial and anti-virulence activity of manuka honey against genetically diverse Staphylococcus pseudintermedius strains. Applied and Environmental Microbiology, 86(e01768-20)

   https://doi.org/10.1128/aem.01768-20, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54999
6. Patchanee, P., Tanamai, P., Tadee, P., Hitchings, M., Calland, J., Sheppard, S., Meunsene, D., Pascoe, B., & Tadee, P. (2020). Whole-genome characterisation of multidrug resistant monophasic variants of Salmonella Typhimurium from pig production in Thailand. PeerJ, 8, e9700

   https://doi.org/10.7717/peerj.9700, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54978
7. Pascoe, B., Schiaffino, F., Murray, S., Méric, G., Bayliss, S., Hitchings, M., Mourkas, E., Calland, J., Burga, R., Yori, P., Jolley, K., Cooper, K., Parker, C., Olortegui, M., Kosek, M., & Sheppard, S. (2020). Genomic epidemiology of Campylobacter jejuni associated with asymptomatic pediatric infection in the Peruvian Amazon. PLOS Neglected Tropical Diseases, 14(8), e0008533

   https://doi.org/10.1371/journal.pntd.0008533, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54977
8. Mourkas, E., Taylor, A., Méric, G., Bayliss, S., Pascoe, B., Mageiros, L., Calland, J., Hitchings, M., Ridley, A., Vidal, A., Forbes, K., Strachan, N., Parker, C., Parkhill, J., Jolley, K., Cody, A., Maiden, M., Kelly, D., & Sheppard, S. (2020). Agricultural intensification and the evolution of host specialism in the enteric pathogen Campylobacter jejuni. Proceedings of the National Academy of Sciences, 117(20), 11018-11028.

   https://doi.org/10.1073/pnas.1917168117, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54261
9. Cunningham, A., Hitchings, M., Stephens, J., Luzio, S., & Harris, D. (2020). Tu1933 THE CHALLENGES IN DEVELOPING A FAECAL TRANSPLANTATION BANK FOR THE TREATMENT OF OBESITY AND TYPE TWO DIABETES. Gastroenterology, 158(6), S-1223.

   https://doi.org/10.1016/s0016-5085(20)33720-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56202
10. Mourkas, E., Florez‐Cuadrado, D., Pascoe, B., Calland, J., Bayliss, S., Mageiros, L., Méric, G., Hitchings, M., Quesada, A., Porrero, C., Ugarte‐Ruiz, M., Gutiérrez‐Fernández, J., Domínguez, L., & Sheppard, S. (2019). Gene pool transmission of multidrug resistance among Campylobacter from livestock, sewage and human disease. Environmental Microbiology, 21(12), 4597-4613.

    https://doi.org/10.1111/1462-2920.14760, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52190
11. Hitchings, M., Cunningham, A., Chandler, S., & Harris, D. (2019). The Challenges in developing a Faecal Transplantation Bank for the Treatment of IBD. In Falk Foundation Symposium 217: West Meets East: Functional Meets Organic in Gastrointestinal Diseases

    SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53364

    http://www.falk-foundation-symposia.org/symposia-and-workshops/2019/?L=1
12. Hitchings, M., Chandler, S., Cunningham, A., & Harris, D. (2019). A National Survey of IBD Clinician’s Perspectives on the Use of Faecal Microbiota Transplantation. In Falk Foundation Symposium 217 West Meets East: Functional Meets Organic in Gastrointestinal Diseases

    SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53365

    http://www.falk-foundation-symposia.org/symposia-and-workshops/2019/?L=1
13. Pascoe, B., Williams, L., Calland, J., Meric, G., Hitchings, M., Dyer, M., Ryder, J., Shaw, S., Lopes, B., Chintoan-Uta, C., Allan, E., Vidal, A., Fearnley, C., Everest, P., Pachebat, J., Cogan, T., Stevens, M., Humphrey, T., Wilkinson, T...., & Sheppard, S. (2019). Domestication of Campylobacter jejuni NCTC 11168. Microbial Genomics, 5(7)

    https://doi.org/10.1099/mgen.0.000279, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51148
14. Royden, A., Ormandy, E., Pinchbeck, G., Pascoe, B., Hitchings, M., Sheppard, S., & Williams, N. (2019). Prevalence of faecal carriage of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli in veterinary hospital staff and students. Veterinary Record Open, 6(1), e000307

    https://doi.org/10.1136/vetreco-2018-000307, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48073
15. Wilkinson, T., Jenkins, G., Davies, A., Row, P., Hitchings, M., & Islam, S. (2018). Protocol for faecal microbiota transplantation in ulcerative colitis (FMTUC): a randomised feasibility study. BMJ Open

    https://doi.org/10.1136/bmjopen-2018-021987, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa45409
16. Terra, L., Dyson, P., Hitchings, M., Thomas, L., Abdelhameed, A., Banat, I., Gazze, S., Vujaklija, D., Facey, P., Francis, L., Quinn, G., & Dyson, P. (2018). A Novel Alkaliphilic Streptomyces Inhibits ESKAPE Pathogens. Frontiers in Microbiology, 9

    https://doi.org/10.3389/fmicb.2018.02458, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa44961

    http://dx.doi.org/10.3389/fmicb.2018.02458
17. Uren Webster, T., Consuegra, S., Hitchings, M., Garcia De Leaniz, C., & Consuegra del Olmo, S. (2018). Interpopulation Variation in the Atlantic Salmon Microbiome Reflects Environmental and Genetic Diversity. Applied and Environmental Microbiology, 84(16)

    https://doi.org/10.1128/AEM.00691-18, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa40815
18. Berthenet, E., Yahara, K., Thorell, K., Pascoe, B., Meric, G., Mikhail, J., Engstrand, L., Enroth, H., Burette, A., Megraud, F., Varon, C., Atherton, J., Smith, S., Wilkinson, T., Hitchings, M., Falush, D., & Sheppard, S. (2018). A GWAS on Helicobacter pylori strains points to genetic variants associated with gastric cancer risk. BMC Biology, 16(1)

    https://doi.org/10.1186/s12915-018-0550-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43222
19. Zhang, B., Tang, S., Chen, X., Zhang, G., Zhang, W., Chen, T., Liu, G., Li, S., Dos Santos, L., Castro, H., Facey, P., Hitchings, M., & Dyson, P. (2018). Streptomyces qaidamensis sp. nov., isolated from sand in the Qaidam Basin, China. The Journal of Antibiotics

    https://doi.org/10.1038/s41429-018-0080-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa41085
20. Hitchings, M. (2018). High Resolution Whole Genome Multilocus Sequence Typing (wgMLST) Schemes for Salmonella enterica Weltevreden Epidemiologic Investigations. Microbiology and Biotechnology Letters, 46(2), 162-162.

    https://doi.org/10.4014/mbl.1802.02008, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa40988

    http://www.mbl.or.kr/
21. Hitchings, M. (2017). PHENOTYPIC AND GENOTYPIC CHARACTERISATION OF STAPHYLOCOCCUS EPIDERMIDIS FROM ORTHOPAEDIC DEVICE-RELATED INFECTIONS CORRELATED WITH PATIENT OUTCOME. In Orthopaedic Proceedings: A supplement to The Bone & Joint Journal (pp. SUPP.22-65).

    SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38074

    http://bjjprocs.boneandjoint.org.uk/content/99-B/SUPP_22/65
22. Chen, X., Hitchings, M., Mendoza, J., Balanza, V., Facey, P., Dyson, P., Bielza, P., Sol, R., & Del Sol Abascal, R. (2017). Comparative Genomics of Facultative Bacterial Symbionts Isolated from European Orius Species Reveals an Ancestral Symbiotic Association. Frontiers in Microbiology, 8

    https://doi.org/10.3389/fmicb.2017.01969, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35991
23. Post, V., Harris, L., Morgenstern, M., Mageiros, L., Hitchings, M., Méric, G., Pascoe, B., Sheppard, S., Richards, R., & Moriarty, T. (2017). Comparative Genomics Study of Staphylococcus epidermidis Isolates from Orthopedic-Device-Related Infections Correlated with Patient Outcome. Journal of Clinical Microbiology, 55(10), 3089-3103.

    https://doi.org/10.1128/JCM.00881-17, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35058

    https://researchportal.bath.ac.uk/en/publications/a-comparative-genomics-study-of-istaphylococcus-epidermidisi-from
24. Pascoe, B., Méric, G., Yahara, K., Wimalarathna, H., Murray, S., Hitchings, M., Sproston, E., Carrillo, C., Taboada, E., Cooper, K., Huynh, S., Cody, A., Jolley, K., Maiden, M., McCarthy, N., Didelot, X., Parker, C., & Sheppard, S. (2017). Local genes for local bacteria: Evidence of allopatry in the genomes of transatlantic Campylobacter populations. Molecular Ecology, 26(17), 4497-4508.

    https://doi.org/10.1111/mec.14176, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa33686
25. Murray, S., Pascoe, B., Méric, G., Mageiros, L., Yahara, K., Hitchings, M., Friedmann, Y., Wilkinson, T., Gormley, F., Mack, D., Bray, J., Lamble, S., Bowden, R., Jolley, K., Maiden, M., Wendlandt, S., Schwarz, S., Corander, J., Fitzgerald, J., & Sheppard, S. (2017). Recombination-Mediated Host Adaptation by Avian Staphylococcus aureus. Genome Biology and Evolution, 9(4), 830-842.

    https://doi.org/10.1093/gbe/evx037, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52398
26. Vale, F., Nunes, A., Oleastro, M., Gomes, J., Sampaio, D., Rocha, R., Vítor, J., Engstrand, L., Pascoe, B., Berthenet, E., Sheppard, S., Hitchings, M., Mégraud, F., Vadivelu, J., & Lehours, P. (2017). Genomic structure and insertion sites of Helicobacter pylori prophages from various geographical origins. Scientific Reports, 7, 42471

    https://doi.org/10.1038/srep42471, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa32006

    http://rdcu.be/pi0q
27. Rossi, G., Silva, H., Aguilar, C., Rochetti, A., Pascoe, B., Méric, G., Mourkas, E., Hitchings, M., Mathias, L., Ruiz, V., Fukumasu, H., Sheppard, S., & Vidal, A. (2017). Comparative genomic survey of Bacillus cereus sensu stricto isolates from the dairy production chain in Brazil. FEMS Microbiology Letters

    https://doi.org/10.1093/femsle/fnx283, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38380

    https://doi.org/10.1093/femsle/fnx283
28. Sankar, A., Bayliss, S., Feil, E., Corander, J., Pascoe, B., Méric, G., Honkela, A., Hitchings, M., Malone, B., & Sheppard, S. (2016). Bayesian identification of bacterial strains from sequencing data. Microbial Genomics, 2(8)

    https://doi.org/10.1099/mgen.0.000075, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26788
29. Culebro, A., Revez, J., Pascoe, B., Friedmann, Y., Hitchings, M., Stupak, J., Sheppard, S., Li, J., Rossi, M., Pascoe, B., Friedmann, Y., & Hitchings, M. (2016). Large Sequence Diversity within the Biosynthesis Locus and Common Biochemical Features of Campylobacter coli Lipooligosaccharides. Journal of Bacteriology, 198(20), 2829-2840.

    https://doi.org/10.1128/jb.00347-16, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27686
30. Méric, G., Hitchings, M., Pascoe, B., & Sheppard, S. (2016). From Escherich to the Escherichia coli genome. The Lancet Infectious Diseases, 16(6), 634-636.

    https://doi.org/10.1016/S1473-3099(16)30066-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28958
31. Hitchings, M. (2016). Disease severity associated genomic variation among Campylobacter jejuni isolates from asymptomatic and acute infection in children of the Peruvian Amazon. In European Congress of Clinical Microbiology and Infectious Diseases 2016

    SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27687

    http://eccmidlive.org/#resources/disease-severity-associated-genomic-variation-among-campylobacter-jejuni-isolates-from-asymptomatic-and-acute-infection-in-children-of-the-peruvian-amazon
32. Sun, H., Gao, T., Chen, X., Hitchings, M., Li, S., Chen, T., Zhang, H., An, L., & Dyson, P. (2016). Complete genome sequence of a psychotrophic Arthrobacter strain A3 (CGMCC 1.8987), a novel long-chain hydrocarbons producer. Journal of Biotechnology, 222, 23-24.

    https://doi.org/10.1016/j.jbiotec.2016.02.010, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26369
33. Del Sol Abascal, R., Dyson, P., Walker (neeWhitten), M., Hitchings, M., Facey, P., & Meric, G. (2015). Draft genomes, phylogenetic reconstruction and comparative genomics of two novel cohabiting bacterial symbionts isolated from Frankliniella occidentalis.. Genome Biology and Evolution

    https://doi.org/10.1093/gbe/evv136, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa22772

    http://gbe.oxfordjournals.org/content/early/2015/07/15/gbe.evv136.long
34. Del Sol , R., Jones, H., Dyson, P., Del Sol Abascal, R., Hitchings, M., & Facey, P. (2014). A tale of tails: deciphering the contribution of terminal tails to the biochemical properties of two Dps proteins from Streptomyces coelicolor.. Cell Mol Life Sci

    https://doi.org/10.1007/s00018-014-1658-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18070
35. Dale, C., Facey, P., Hitchings, M., Williams, J., Skibinski, D., Dyson, P., Sol, R., & Del Sol Abascal, R. (2013). The Evolution of an Osmotically Inducible dps in the Genus Streptomyces. PLoS ONE, 8(4)

    https://doi.org/10.1371/journal.pone.0060772, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa14547
36. Facey, P., Sevcikova, B., Novakova, R., Hitchings, M., Crack, J., Kormanec, J., Dyson, P., & Sol, R. (2011). Correction: The dpsA Gene of Streptomyces coelicolor: Induction of Expression from a Single Promoter in Response to Environmental Stress or during Development. PLoS ONE, 6(11)

    https://doi.org/10.1371/annotation/8fedd9bb-d84e-4d7b-bc71-3321e652198d, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa24209
37. Hitchings, M., Facey, P., Sevikova, B., Novakova, R., Hitchings, M., Crack, J., Kormanec, J., Dyson, P., Abascal, R., Dyson, P., Del Sol Abascal, R., & Facey, P. (2011). The dpsA Gene of Streptomyces coelicolor: Induction of Expression from a Single Promoter in Response to Environmental Stress or during. PlosOne, 6(9), e25593

    https://doi.org/10.1371/journal.pone.0025593, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10243
38. Facey, P., Hitchings, M., Saavedra-Garcia, P., Fernandez-Martinez, L., Dyson, P., Abascal, R., Dyson, P., Del Sol Abascal, R., Hitchings, M., & Facey, P. (2009). Streptomyces coelicolor Dps-like proteins: Differential dual roles in response to stress during vegetative growth and in nucleoid condensation during reproductive cell division. Molecular Microbiology, 73(6), 1186-202.

    https://doi.org/10.1111/j.1365-2958.2009.06848.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9837
39. Pascoe, B., Schiaffino, F., Murray, S., Meric, G., Bayliss, S., Hitchings, M., Mourkas, E., Calland, J., Burga, R., Yori, P., Jolley, K., Cooper, K., Parker, C., Olortegui, M., Kosek, M., & Sheppard, S. (n.d.) Genomic epidemiology of Campylobacter jejuni associated with asymptomatic paediatric infection in the Peruvian Amazon

    https://doi.org/10.1101/2020.04.26.20075689, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54262
40. Saud, Z., Hitchings, M., & Butt, T. (2021). Nanopore sequencing and de novo assembly of a misidentified Camelpox vaccine reveals putative epigenetic modifications and alternate protein signal peptides. Scientific Reports, 11(1)

    https://doi.org/10.1038/s41598-021-97158-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58104
41. Mourkas, E., Yahara, K., Bayliss, S., Calland, J., Johansson, H., Mageiros, L., Muñoz-Ramirez, Z., Futcher, G., Méric, G., Hitchings, M., Sandoval-Motta, S., Torres, J., Jolley, K., Maiden, M., Ellström, P., Waldenström, J., Pascoe, B., & Sheppard, S. (2022). Host ecology regulates interspecies recombination in bacteria of the genus Campylobacter. eLife, 11

    https://doi.org/10.7554/elife.73552, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59565
42. Andongma, A., WHITTEN, M., Del Sol Abascal, R., Hitchings, M., & Dyson, P. (2022). Bacterial Competition Influences the Ability of Symbiotic Bacteria to Colonize Western Flower Thrips. Frontiers in Microbiology, 13

    https://doi.org/10.3389/fmicb.2022.883891, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60193
43. Del Sol Abascal, R., Walker (neeWhitten), M., Xue, Q., Taning, C., James, R., Smagghe, G., Sol, R., Hitchings, M., & Dyson, P. (2023). A narrow host-range and lack of persistence in two non-target insect species of a bacterial symbiont exploited to deliver insecticidal RNAi in Western Flower Thrips. Frontiers in Insect Science, 3

    https://doi.org/10.3389/finsc.2023.1093970, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62479
44. Mouftah, S., Pascoe, B., Calland, J., Mourkas, E., Tonkin, N., Lefevre, C., Deuker, D., Smith, S., Wickenden, H., Hitchings, M., Sheppard, S., & Elhadidy, M. (2022). Local accessory gene sharing among Egyptian Campylobacter potentially promotes the spread of antimicrobial resistance. Microbial Genomics, 8(6)

    https://doi.org/10.1099/mgen.0.000834, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63742

    http://dx.doi.org/10.1099/mgen.0.000834
45. Kittiwan, N., Calland, J., Mourkas, E., Hitchings, M., Murray, S., Tadee, P., Tadee, P., Duangsonk, K., Meric, G., Sheppard, S., Patchanee, P., & Pascoe, B. (2022). Genetic diversity and variation in antimicrobial-resistance determinants of non-serotype 2 Streptococcus suis isolates from healthy pigs. Microbial Genomics, 8(11)

    https://doi.org/10.1099/mgen.0.000882, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63744

    http://dx.doi.org/10.1099/mgen.0.000882
46. Facey, P., Sevcikova, B., Novakova, R., Hitchings, M., Crack, J., Kormanec, J., Dyson, P., & Del Sol Abascal, R. (2011). Correction: The dpsA Gene of Streptomyces coelicolor: Induction of Expression from a Single Promoter in Response to Environmental Stress or during Development. PLoS ONE, 6(11)

    https://doi.org/10.1371/annotation/8fedd9bb-d84e-4d7b-bc71-3321e652198d, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63747

    http://dx.doi.org/10.1371/annotation/8fedd9bb-d84e-4d7b-bc71-3321e652198d
47. Holt, A., Najumudeen, A., Collard, T., Li, H., Millett, L., Hoskin, A., Legge, D., Mortensson, E., Flanagan, D., Jones, N., Kollareddy, M., Timms, P., Hitchings, M., Cronin, J., Sansom, O., Williams, A., & Vincent, E. (2023). Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition. Cancer and Metabolism, 11(1)

    https://doi.org/10.1186/s40170-023-00318-y, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65574
48. Anka, I., Uren Webster, T., Berbel-Filho, W., Hitchings, M., Overland, B., Weller, S., Garcia De Leaniz, C., & Consuegra del Olmo, S. (2024). Microbiome and epigenetic variation in wild fish with low genetic diversity. Nature Communications, 15(1)

    https://doi.org/10.1038/s41467-024-49162-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa67975

    http://dx.doi.org/10.1038/s41467-024-49162-8

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